Sensitivity Analysis of a 2D Stochastic Agent-Based and PDE Diffusion Model for Cancer-on-Chip Experiments

The present work extends a previous paper where an agent-based and two-dimensional partial differential diffusion model was introduced for describing immune cell dynamics (leukocytes) in cancer-on-chip experiments. In the present work, new features are introduced for the dynamics of leukocytes and for their interactions with tumor cells, improving the adherence of the model to what is observed in laboratory experiments. Each system's solution realization is a family of biased random walk trajectories, affected by the chemotactic gradients and in turn affecting them.

Pinned Flexible Polymer under Oscillatory Linear Flow

The non-equilibrium structural and dynamical properties of a flexible polymer pinned to a reflecting wall and subject to oscillatory linear flow are studied by numerical simulations. Polymer is confined in two dimensions and is modeled as a bead-spring chain while the interaction with the fluid is described by the Brownian multiparticle collision dynamics. At low strain the polymer is stretched along the flow direction. When increasing strain, chains are completely elongated and compressed against the wall when the flow is reverted.

Prisma Noise Coefficients Estimation

The PRISMA (PRecursore IperSpettrale della Missione Applicativa) hyperspectral satellite, launched by the Italian Space Agency (ASI) is presently operational on a global scale. The mission includes the hyperspectral imager PRISMA working in the 400-2500 nm spectral range with 234 bands and a panchromatic (PAN) camera (400-750 nm). In the context of this work, we intend to determine the two noise components (photon and thermal noise) and assess SNR with an image based approach.

Numerical Rock-Glacier Flow via the Pressure Method

Recent literature confirms the crucial influence of non-viscous deformations together with temperature impact on glacier and rock glacier flow numerical simulation. Along this line, supported by the successful test on a one-dimensional set-up developed by two of the author, we propose the numerical solution of a two-dimensional rock-glacier flow model based on an ice constitutive law of second grade differential type .

Approximate Method to Compute Hypersingular Finite-Part Integrals with Rapidly Oscillating Kernels

In this paper, an algorithm for the numerical evaluation of hypersingular finite-part integrals with rapidly oscillating kernels is proposed. The method is based on an interpolatory procedure at zeros of the orthogonal polynomials with respect to the first kind Chebyshev weight. Bounds of the error and of the amplification factor are also provided. Numerically stable procedure are obtained and the corresponding algorithms can be implemented in a fast way.

A Novel Fractional-Order RothC Model

A new fractional q-order variation of the RothC model for the dynamics of soil organic carbon is introduced. A computational method based on the discretization of the analytic solution along with the finite-difference technique are suggested and the stability results for the latter are given. The accuracy of the scheme, in terms of the temporal step size h, is confirmed through numerical testing of a constructed analytic solution. The effectiveness of the proposed discrete method is compared with that of the classical discrete RothC model.

A Molecular Dynamics Study of the Evolving Melt Front under Gravity

During melting under gravity in the presence of a horizontal thermal gradient, buoyancy-driven convection in the liquid phase affects significantly the evolution of the liquid-solid interface. Due to the obvious engineering interest in understanding and controlling melting processes, fluid dynamicists and applied mathematicians have spent many efforts to model and simulate them numerically. Their endeavors concentrated in the twenty-five years period between the publication of the paper by Brent, Voller & Reid (1988) and that by Mansutti & Bucchignani (2011).