The present work extends a previous paper where an agent-based and two-dimensional partial differential diffusion model was introduced for describing immune cell dynamics (leukocytes) in cancer-on-chip experiments. In the present work, new features are introduced for the dynamics of leukocytes and for their interactions with tumor cells, improving the adherence of the model to what is observed in laboratory experiments. Each system's solution realization is a family of biased random walk trajectories, affected by the chemotactic gradients and in turn affecting them.

The PRISMA (PRecursore IperSpettrale della Missione Applicativa) hyperspectral satellite, launched by the Italian Space Agency (ASI) is presently operational on a global scale. The mission includes the hyperspectral imager PRISMA working in the 400-2500 nm spectral range with 234 bands and a panchromatic (PAN) camera (400-750 nm). In the context of this work, we intend to determine the two noise components (photon and thermal noise) and assess SNR with an image based approach.

Usually, clinicians assess the correct hemodynamic behavior and fetal wellbeing during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach has demonstrated to be satisfactory in the most of the cases, it can be largely improved with the aid of more advanced techniques, i.e. numerical analysis and simulation. Another key aspect limiting the analysis is that clinicians rely on a limited number of Doppler waveforms observed during the clinical examination.

Regular physical exercise and appropriate nutrition affect metabolic and hormonal responses and may reduce the risk of developing chronic non-communicable diseases such as high blood pressure, ischemic stroke, coronary heart disease, some types of cancer, and type 2 diabetes mellitus. Computational models describing the metabolic and hormonal changes due to the synergistic action of exercise and meal intake are, to date, scarce and mostly focussed on glucose absorption, ignoring the contribution of the other macronutrients.

In this paper, a complete picture of the different plastic failure modes that can be predicted by the strain gradient plasticity model proposed in Del Piero et al. (J. Mech. Mater. Struct. 8:109-151, 2013) is drawn. The evolution problem of the elasto-plastic strain is formulated in Del Piero et al. (J. Mech. Mater. Struct. 8:109-151, 2013) as an incremental minimization problem acting on an energy functional which includes a local plastic term and a non-local gradient contribution.

Vitamin D has been proven to be a strong stimulator of mechanisms associated with the elimination of pathogens. Because of its recognized effectiveness against viral infections, during SARS-CoV-2 infection, the effects of Vitamin D supplementation have been the object of debate. This study aims to contribute to this debate by the means of a qualitative phenomenological mathematical model in which the role of Vitamin D and its interactions with the innate immune system are explicitly considered.

In this paper, an algorithm for the numerical evaluation of hypersingular finite-part integrals with rapidly oscillating kernels is proposed. The method is based on an interpolatory procedure at zeros of the orthogonal polynomials with respect to the first kind Chebyshev weight. Bounds of the error and of the amplification factor are also provided. Numerically stable procedure are obtained and the corresponding algorithms can be implemented in a fast way.

We consider here a cell-centered finite difference approximation of the Richards equation in three dimensions, averaging for interface values the hydraulic conductivity, a highly nonlinear function, by arithmetic, upstream and harmonic means. The nonlinearities in the equation can lead to changes in soil conductivity over several orders of magnitude and discretizations with respect to space variables often produce stiff systems of differential equations.