| |
|
In recent years there has been a widespread interest in researching biomarkers of aging that could predict physiological vulnerability better than chronological age. Aging, in fact, is one of the most relevant risk factors for a wide range of maladies, and molecular surrogates of this phenotype… |
| |
|
|
| |
|
This paper investigates the problem of quantifying the impact of unex- pected deviations of mortality trend on a longevity indexed life annuity in a Solvency II perspective. Solvency II quantitative requirements regulate the margins required to offset the insurance risk in a one year risk horizon.… |
| |
|
An integrated software tool environment is presented, and a methodology is proposed for the operational support of the local authority, for analysis of the impact of transport measures in terms of network energy consumption and pollutant emissions. It is based on work done by the European Union… |
| |
|
Community structure is an important topological phenomenon typical of complex networks. Accurately unveiling communities is thus crucial to understand and capture the many-faceted nature of complex networks. Communities in real world frequently overlap, i.e. nodes can belong to more than one… |
| |
|
|
| |
|
The beneficial effects of physical activity for the prevention and management of several chronic diseases are widely recognized. Mathematical modeling of the effects of physical exercise in body metabolism and in particular its influence on the control of glucose homeostasis is of primary… |
| |
|
Remote sensing of atmosphere is changing rapidly thanks to the development of high spectral resolution infrared space-born sensors. The aim is to provide more and more accurate information on the lower atmosphere, as requested by the World Meteorological Organization (WMO), to improve reliability… |
| |
|
We present and release in open source format a sparse linear solver which efficiently exploits heterogeneous parallel computers. The solver can be easily integrated into scientific applications that need to solve large and sparse linear systems on modern parallel computers made of hybrid nodes… |
| |
|
An innovative analytical/computational approach is presented to provide maximum allowed
probabilities (MAPs) of conformations in protein domains not rigidly connected. The approach is applied to
calmodulin and to its adduct with R-synuclein. Calmodulin is a protein constituted by two rigid domains… |
