
Stringent error estimates for one-dimensional, space-dependent 2 x 2 relaxation systems
Sharp and local L-1 a posteriori error estimates are established for so-called "well-balanced" BV (hence possibly discontinuous) numerical approximations of 2 x 2 space-dependent Jin-Xin relaxation systems under sub-characteristic condition.
Dynamic mesh refinement for discrete models of jet electro-hydrodynamics
Nowadays, several models of unidimensional fluid jets exploit discrete element methods. In some cases,
as for models aiming at describing the electrospinning nanofabrication process of polymer fibers, discrete
element methods suffer a non-constant resolution of the jet representation. We develop a dynamic mesh-
refinement method for the numerical study of the electro-hydrodynamic behavior of charged jets using
discrete element methods. To this purpose, we import ideas and techniques from the string method
originally developed in the framework of free-energy landscape simulations.
Altered brain criticality in Schizophrenia: New insights from MEG
Schizophrenia has a complex etiology and symptomatology that is difficult to untangle. After decades of research, important advancements towards a central biomarker are still lacking. One of the missing pieces is a better understanding of how non-linear neural dynamics are altered in this patient population. In this study, the resting-state neuromagnetic signals of schizophrenia patients and healthy controls were analyzed in the framework of criticality.
Mathematical tools for controlling invasive species in Protected Areas
A challenging task in the management of Protected Areas is the conservation of natural habitats and native endangered species through the optimization of control strategies for invasive plant or animal species, typically competing for the use of resources in a fragmented habitat [1]. We review two cases of control strategies on the wolf-wild boar populations in a Southern Italy Protected Area belonging to the Natura 2000 network [2,3].
Distinct Antigen Delivery Systems Induce Dendritic Cells' Divergent Transcriptional Response: New Insights from a Comparative and Reproducible Computational Analysis.
Vaccination is the most successful and cost-effective method to prevent infectious diseases. However, many vaccine antigens have poor in vivo immunogenic potential and need adjuvants to enhance immune response. The application of systems biology to immunity and vaccinology has yielded crucial insights about how vaccines and adjuvants work. We have previously characterized two safe and powerful delivery systems derived from non-pathogenic prokaryotic organisms: E2 and fd filamentous bacteriophage systems.
Neural oscillations track natural but not artificial fast speech: Novel insights from speech-brain coupling using MEG
Neural oscillations contribute to speech parsing via cortical tracking of hierarchical linguistic structures, including syllable rate. While the properties of neural entrainment have been largely probed with speech stimuli at either normal or artificially accelerated rates, the important case of natural fast speech has been largely overlooked. Using magnetoencephalography, we found that listening to naturally-produced speech was associated with cortico-acoustic coupling, both at normal (~6 syllables/s) and fast (~9 syllables/s) rates, with a corresponding shift in peak entrainment frequency.
Semiflexible polymers under oscillatory shear flow
The non-equilibrium structural and dynamical properties of semiflexible polymers confined to
two dimensions under oscillatory shear flow are investigated by Brownian multi-particle collision
dynamics. Two different scenarios will be considered: Filaments with both fixed ends [1] and
wall-anchored chains [2]. The results of the numerical studies will be presented and discussed.
References
[1] A. Lamura, R. G. Winkler Polymers 2019, 11, 737. DOI:10.3390/polym11040737
[2] A. Lamura, R. G. Winkler, G. Gompper pre-print 2021
Gamma-Convergence Analysis of a Generalized XY Model: Fractional Vortices and String Defects
We propose and analyze a generalized two dimensional XY model, whose interaction potential has n weighted wells, describing corresponding symmetries of the system. As the lattice spacing vanishes, we derive by -convergence the discrete-to-continuum limit of this model. In the energy regime we deal with, the asymptotic ground states exhibit fractional vortices, connected by string defects. The -limit takes into account both contributions, through a renormalized energy, depending on the configuration of fractional vortices, and a surface energy, proportional to the length of the strings.





