Conformational variability and heterogeneity are crucial determinants of the function of biological macromolecules. The possibility of accessing this information experimentally suffers from severe under-determination of the problem, since there are a few experimental observables to be accounted for by a (potentially) infinite number of available conformational states. Several computational methods have been proposed over the years in order to circumvent this theoretically insurmountable obstacle.

In a computer-aided system for skin cancer diagnosis, hair removal is one of the main challenges to face before applying a process of automatic skin lesion segmentation and classification. In this paper, we propose a straightforward method to detect and remove hair from dermoscopic images. Preliminarily, the regions to consider as candidate hair regions and the border/corner components located on the image frame are automatically detected. Then, the hair regions are determined using information regarding the saliency, shape and image colors.

We study numerically the effect of thermal fluctuations and of variable fluid-substrate interactions on the spontaneous dewetting of thin liquid films. To this aim, we use a recently developed lattice Boltzmann method for thin liquid film flows, equipped with a properly devised stochastic term. While it is known that thermal fluctuations yield shorter rupture times, we show that this is a general feature of hydrophilic substrates, irrespective of the contact angle $\theta$. The ratio between deterministic and stochastic rupture times, though, decreases with $\theta$.

The Global Navigation Satellite System (GNSS) meteorology contribution to the comprehension of the Earth's atmosphere's global and regional variations is essential. In GNSS processing, the zenith wet delay is obtained using the difference between the zenith total delay and the zenith hydrostatic delay. The zenith wet delay can also be converted into precipitable water vapor by knowing the atmospheric weighted mean temperature profiles.

The problem of the computation of stereo disparity is approaehed as a mathematically ill-posed problem by using regularization theory. A controlled continuity constraint which provides a local spatial control over the smoothness of the solution enables the problem to be regularized while preserving the disparity discontinuities. The discontinuities are localized during the regularization process by examining the size of the disparity gradient at the gray value edges.

Operated by the H2020 SOMA Project, the recently established Social Observatory for Disinformation and Social Media Analysis supports researchers, journalists and fact-checkers in their quest for quality information. At the core of the Observatory lies the DisInfoNet Toolbox, designed to help a wide spectrum of users understand the dynamics of (fake) news dissemination in social networks. DisInfoNet combines text mining and classification with graph analysis and visualization to offer a comprehensive and user-friendly suite.