Front propagation in two-dimensional steady and unsteady cellular flows is investigated in the limit of very fast reaction and sharp front, i.e., in the geometrical optics limit. For the steady flow, a simplified model allows for an analytical prediction of the front speed v(f) dependence on the stirring intensity U, which is in good agreement with numerical estimates. In particular, at large U, the behavior v(f)similar toU/log(U) is predicted. By adding small scales to the velocity field we found that their main effect is to renormalize the flow intensity.

Bioventing is a technology used to abate the presence of pollutants in the subsoil. Microorganisms biodegrade the pollutant but the biochemical reaction requires oxygen and so an airflow is induced in the subsoil by means of injection and/or extraction wells. Costs, final result and decontamination time are reliant on contaminant type, soil permeability and several other factors, but oxygen subsoil concentration plays a very important role.

In this article, a methodology to retrieve the precipitable water vapor (PWV) from a differential interferometric time series is presented. We used external data provided by atmospheric weather models (e.g., ERA-Interim reanalysis) to constrain the initial state and by Global Navigation Satellite System (GNSS) to phase ambiguities elimination introduced by phase unwrapping algorithm. An iterative least-square is then used to solve the optimization problem.

Tumor resistance to chemotherapy represents an important challenge in modern oncology. Although platinum (Pt)-based drugs have demonstrated excellent therapeutic potential, their effectiveness in a wide range of tumors is limited by the development of resistance mechanisms. One of these mechanisms includes increased cisplatin sequestration/efflux by the copper-transporting ATPase, ATP7B. However, targeting ATP7B to reduce Pt tolerance in tumors could represent a serious risk because suppression of ATP7B might compromise copper homeostasis, as happens in Wilson disease.