Nonlocal PageRank

In this work we introduce and study a nonlocal version of the PageRank. In our approach, the random walker explores the graph using longer excursions than just moving between neighboring nodes. As a result, the corresponding ranking of the nodes, which takes into account a long-range interaction between them, does not exhibit concentration phenomena typical of spectral rankings which take into account just local interactions. We show that the predictive value of the rankings obtained using our proposals is considerably improved on different real world problems.

Sixth post-Newtonian local-in-time dynamics of binary systems

Using a recently introduced method [D. Bini, T. Damour, and A. Geralico, Phys. Rev. Lett. 123, 231104 (2019)], which splits the conservative dynamics of gravitationally interacting binary systems into a nonlocal-in-time part and a local-in-time one, we compute the local part of the dynamics at the sixth post-Newtonian (6PN) accuracy. Our strategy combines several theoretical formalisms: post-Newtonian, post-Minkowskian, multipolar-post-Minkowskian, effective-field-theory, gravitational self-force, effective one-body, and Delaunay averaging.

A tight relation between series-parallel graphs and bipartite distance hereditary graphs

Bandelt and Mulder's structural characterization of bipartite distance hereditary graphs 16 asserts that such graphs can be built inductively starting from a single vertex and by re- 17 peatedly adding either pendant vertices or twins (i.e., vertices with the same neighborhood 18 as an existing one). Dirac and Duffin's structural characterization of 2-connected series- 19 parallel graphs asserts that such graphs can be built inductively starting from a single edge 20 by adding either edges in series or in parallel.

Patient, interrupted: MEG oscillation dynamics reveal temporal dysconnectivity in schizophrenia

Current theories of schizophrenia emphasize the role of altered information integration as the core dysfunction of this illness. While ample neuroimaging evidence for such accounts comes from investigations of spatial connectivity, understanding temporal disruptions is important to fully capture the essence of dysconnectivity in schizophrenia.

Synthetic Lethality Screening Identifies FDA-Approved Drugs That Overcome ATP7B-Mediated Tolerance of Tumor Cells to Cisplatin

Tumor resistance to chemotherapy represents an important challenge in modern oncology. Although platinum (Pt)-based drugs have demonstrated excellent therapeutic potential, their effectiveness in a wide range of tumors is limited by the development of resistance mechanisms. One of these mechanisms includes increased cisplatin sequestration/efflux by the copper-transporting ATPase, ATP7B. However, targeting ATP7B to reduce Pt tolerance in tumors could represent a serious risk because suppression of ATP7B might compromise copper homeostasis, as happens in Wilson disease.

On the limit as $s\to 1^-$ of possibly non-separable fractional Orlicz-Sobolev spaces

Extended versions of the Bourgain-Brezis-Mironescu theorems on the limit as s->1^- of the Gagliardo-Slobodeckij fractional seminorm are established in the Orlicz space setting. Our results hold for fractional Orlicz-Sobolev spaces built upon general Young functions, and complement those of [13], where Young functions satisfying the $\Delta_2$ and the $\nabla_2$ conditions are dealt with. The case of Young functions with an asymptotic linear growth is also considered in connection with the space of functions of bounded variation.