Speeding up the DISORT solver: mathematical approach and application to radiance simulations of FORUM

New remote sensing satellite sensors for the measurements of atmospheric radiation offer the advantage of very high spectral resolution and spectral and/or spatial and temporal coverage. The analysis of these measurements often requires a forward model (FM) for the simulation of the radiation collected by the sensor. The FM should model all the processes affecting the radiance, such as absorption and scattering by molecules and particles. Despite the advancement in sensor technology, the radiative transfer solvers are almost the same since several decades.

Visbrain: A multi-purpose GPU-accelerated open-source suite for brain data visualization

We present a Python open-source package called Visbrain that offers a coherent visualization suite for multi-modal brain data (intracranial and scalp EEG, MEG, structural and functional MRI). The current version of Visbrain is essentially articulated around four modules dedicated to 1) 3D visualization of functional and/or connectivity results (Brain), 2) polysomnographic data visualization and sleep analysis (Sleep, [1]), 3) data mining and basic plotting functions (Signal), 4) topographic representation (Topo).

Modelling mass diffusion for a multi-layer sphere immersed in a semi-infinite medium: application to drug delivery

We present a general mechanistic model of mass diffusion for a composite sphere placed in a large ambient medium. The multi-layer problem is described by a system of diffusion equations coupled via interlayer boundary conditions such as those imposing a finite mass resistance at the extemal surface of the sphere. While the work is applicable to the generic problem of heat or mass transfer in a multi-layer sphere, the analysis and results are presented in the context of drug kinetics for desorbing and absorbing spherical microcapsules.

Mechanistic modelling of drug release from multi-layer capsules

We propose a novel in silico model for computing drug release from multi-layer capsules. The diffusion problem in such heterogeneous layer-by-layer composite medium is described by a system of coupled partial differential equations, which we solve analytically using separation of variables. In addition to the conventional partitioning and mass transfer interlayer conditions, we consider a surface finite mass transfer resistance, which corresponds to the case of a coated capsule.

Design and testing of hydrophobic core/hydrophilic shell nano/micro particles for drug-eluting stent coating

In this study, we designed a novel drug-eluting coating for vascular implants consisting of a core coating of the anti-proliferative drug docetaxel ( DTX) and a shell coating of the platelet glycoprotein IIb/IIIa receptor monoclonal antibody SZ-21. The core/shell structure was sprayed onto the surface of 316L stainless steel stents using a coaxial electrospray process with the aim of creating a coating that exhibited a differential release of the two drugs. The prepared stents displayed a uniform coating consisting of nano/micro particles.

CHANGES OF RESTING-STATE OSCILLATORY NETWORK DYNAMICS AFTER MOTOR LEARNING: A M.E.G. DEVELOPMENTAL STUDY

Introduction : Neuroimaging studies have shown that in adults, the motor learning induced alterations of the functional connectivity assessed during Resting State Networks (RSN) is age-dependent (Mary et al., 2017). Motor learning relies on the build-up of new sensori-motor representations, which has been studied using the bar-man task in adults (Barlaam, Vaugoyeau, Fortin, Assaiante, & Schmitz, 2016; Paulignan, Dufossé, Hugon, & Massion, 1989) and in children (Schmitz et al, 2002).. The aim of this study was to investigate the modulations of functional connectivity after a motor learn