A fluid dynamics multidimensional model of biofilm growth: stability, influence of environment and sensitivity

In this article, we study in detail the fluid dynamics system proposed in Clarelli et al. (2013, J. Math. Biol., 66, 1387-1408) to model the formation of cyanobacteria biofilms. After analysing the linear stability of the unique non-trivial equilibrium of the system, we introduce in the model the influence of light and temperature, which are two important factors for the development of a cyanobacteria biofilm.

Mathematical model for transport of DNA plasmids from the external medium up to the nucleus by electroporation

We propose a mathematical model for the transport of DNA plasmids from the extracellular matrix up to the cell nucleus. The model couples two phenomena: the electroporation process, describing the cell membrane permeabilization to plasmids and the intracellular transport enhanced by the presence of microtubules. Numerical simulations of cells with arbitrary geometry, in 2D and 3D, and a network of microtubules show numerically the importance of the microtubules and the electroporation on the effectiveness of the DNA transfection, as observed by previous biological data.

Coherent structures and extreme events in rotating multiphase turbulent flows

By using direct numerical simulations (DNS) at unprecedented resolution, we study turbulence under rotation in the presence of simultaneous direct and inverse cascades. The accumulation of energy at large scale leads to the formation of vertical coherent regions with high vorticity oriented along the rotation axis. By seeding the flowwithmillions ofinertialparticles,wequantify -- forthefirsttime -- theeffects ofthose coherent vertical structures on the preferential concentration of light and heavy particles.

ISODAC: A high performance solution for indexing and searching heterogeneous data

Searching for words or sentences within large sets of textual documents can be very challenging unless an index of the data has been created in advance. However, indexing can be very time consuming especially if the text is not readily available and has to be extracted from files stored in different formats. Several solutions, based on the MapReduce paradigm, have been proposed to accelerate the process of index creation. These solutions perform well when data are already distributed across the hosts involved in the elaboration.

Some applications of the wavelet transform with signal-dependent dilation factor

Time-scale transforms play a fundamental role in the compact representation of signals and images [1]. Non linear time representation provided a significant contribution to the definition of more flexible and adaptive transforms. However, in many applications signals are better characterized in the frequency domain. In particular, frequency distribution in the frequency axis is strictly dependent on the signal under study. On the contrary, frequency axis partition provided by conventional transforms obeys more rigid rules.

The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans

Immunosenescence is thought to result from cellular aging and to reflect exposure to environmental stressors and antigens, including cytomegalovirus (CMV). However, not all of the features of immunosenescence are consistent with this view, and this has led to the emergence of the sister theory of "inflammaging". The recently discovered diffuse tissue distribution of resident memory T cells (TRM) which don't recirculate, calls these theories into question. These cells account for most T cells residing in barrier epithelia which sit in and travel through the extracellular matrix (ECM).