Unravelling the role of phoretic and hydrodynamic interactions in active colloidal suspensions

Active fluids comprise a variety of systems composed of elements immersed in a fluid environment which can convert some form of energy into directed motion; as such they are intrinsically out-of-equilibrium in the absence of any external force. A fundamental problem in the physics of active matter concerns the understanding of how the characteristics of autonomous propulsion and agent-agent interactions determine the collective dynamics of the system.

Synthetic Lethality Screening Identifies FDA-Approved Drugs That Overcome ATP7B-Mediated Tolerance of Tumor Cells to Cisplatin

Tumor resistance to chemotherapy represents an important challenge in modern oncology. Although platinum (Pt)-based drugs have demonstrated excellent therapeutic potential, their effectiveness in a wide range of tumors is limited by the development of resistance mechanisms. One of these mechanisms includes increased cisplatin sequestration/efflux by the copper-transporting ATPase, ATP7B. However, targeting ATP7B to reduce Pt tolerance in tumors could represent a serious risk because suppression of ATP7B might compromise copper homeostasis, as happens in Wilson disease.

Edge Computing Perspectives: Architectures, Technologies, and Open Security Issues

Edge and Fog Computing will be increasingly pervasive in the years to come due to the benefits they bring in many specific use-case scenarios over traditional Cloud Computing. Nevertheless, the security concerns Fog and Edge Computing bring in have not been fully considered and addressed so far, especially when considering the underlying technologies (e.g. virtualization) instrumental to reap the benefits of the adoption of the Edge paradigm. In particular, these virtualization technologies (i.e.

On a class of forward -backward parabolic equations: Formation of singularities

We study the formation of singularities for the problem {u(t) = [phi(u)](xx) + epsilon[psi(u)](txx) in Omega x (0, T) phi(u) + epsilon[psi(u)](t) = 0 in partial derivative Omega x(0, T) u = u(0) >= 0 in Omega x {0}, where epsilon and Tare positive constants, Omega a bounded interval, u(0) a nonnegative Radon measure on Omega, phi a nonmonotone and nonnegative function with phi(0) = phi(infinity) = 0, and psi an increasing bounded function. We show that if u(0) is a bounded or continuous function, singularities may appear spontaneously.

High performance implementations of the 2D Ising model on GPUs

We present and make available novel implementations of the two-dimensional Ising model that is used as a benchmark to show the computational capabilities of modern Graphic Processing Units (GPUs). The rich programming environment now available on GPUs and flexible hardware capabilities allowed us to quickly experiment with several implementation ideas: a simple stencil-based algorithm, recasting the stencil operations into matrix multiplies to take advantage of Tensor Cores available on NVIDIA GPUs, and a highly optimized multi-spin coding approach.

Variation in natural short-period ionospheric noise, and acoustic and gravity waves revealed by the amplitude analysis of a VLF radio signal on the occasion of the Kraljevo earthquake (Mw = 5.4)

We analyse the lower ionosphere disturbances in the time period around the Mw 5.4 Kraljevo earthquake (EQ), which occurred on 3 November 2010 in Serbia. The results presented herein are based on analysis of the amplitudes of three VLF signals emitted in Italy, UK, and Germany and recorded in Serbia whose variations primarily result from changes in the electrical properties of the lower ionosphere at a distance more than 120 km from the epicentre of the EQ.

Data Confidentiality and Availability via Secret Sharing and Node Mobility in UWSN

In Mobile Unattended Wireless Sensor Networks (MUWSNs), nodes sense the environment and store the acquired data until the arrival of a trusted data sink. In this paper, we address the fundamental issue of quantifying to which extent secret sharing schemes, combined with nodes mobility, can help in assuring data availability and confidentiality. We provide accurate analytical results binding the fraction of the network accessed by the sink and the adversary to the amount of information they can successfully recover. Extensive simulations support our findings.

Identification of time-varying inaccessible thermal conductance from data at the boundary

A composite specimen, made of two slabs and an interface A is heated through one of its sides S, in order to evaluate the thermal conductance H of A. The direct model consists of a system of Initial Boundary Value Problems completed by suitable transmission conditions. Thanks to the properties of multilayer diffusion, we reduce the problem to the slab between A and S only. In this case evaluating the thermal resistance of A means to identify a coefficient in a Robin boundary condition. We evaluate H numerically by means of Thin Plate Approximation.