Network and Systems Medicine: Position Paper of the European Collaboration on Science and Technology Action on Open Multiscale Systems Medicine

Introduction: Network and systems medicine has rapidly evolved over the past decade, thanks to computational and integrative tools, which stem in part from systems biology. However, major challenges and hurdles are still present regarding validation and translation into clinical application and decision making for precision medicine.

Optimal Control of Invasive Species with Budget Constraint: Qualitative Analysis and Numerical Approximation

The containment of the invasive species is a widespread problem in the environmental management, with a significant economic impact. We analyze an optimal control model which aims to find the best temporal resource allocation strategy for the removal of an invasive species. We derive the optimality system in the state and control variables and we use the phase-space analysis to provide qualitative insights about the behavior of the optimal solution.

Towards a comprehensive model for the impact of traffic patterns on air pollution

The impact of vehicular traffic on society is huge and multifaceted, including economic, social, health and environmental aspects. The problems is complex and hard to model since it requires to consider traffic patterns, air pollutant emissions, and the chemical reactions and dynamics of pollutants in the low atmosphere. This paper aims at exploring a comprehensive simulation tool ranging from vehicular traffic all the way to environmental impact.