The present work is motivated by the development of a mathematical model mimicking the mechanisms observed in lab-on-chip experiments, made to reproduce on microfluidic chips the in vivo reality. Here we consider the Cancer-on-Chip experiment where tumor cells are treated with chemotherapy drug and secrete chemical signals in the environment attracting multiple immune cell species. The in silico model here proposed goes towards the construction of a "digital twin" of the experimental immune cells in the chip environment to better understand the complex mechanisms of immunosurveillance.

We consider a one-dimensional, isentropic, hydrodynamical model for a unipolar semiconductor, with the mobility depending on the electric field. The mobility is related to the momentum relaxation time, and field-dependent mobility models are commonly used to describe the occurrence of saturation velocity, that is, a limit value for the electron mean velocity as the electric field increases. For the steady state system, we prove the existence of smooth solutions in the subsonic case, with a suitable assumption on the mobility function.

Trust and reputation systems are decision support tools used to drive parties' interactions on the basis of parties' reputation. In such systems, parties rate with each other after each interaction.

We study nonnegative solutions of the Cauchy problem

The containment of the invasive species is a widespread problem in the environmental management, with a significant economic impact. We analyze an optimal control model which aims to find the best temporal resource allocation strategy for the removal of an invasive species. We derive the optimality system in the state and control variables and we use the phase-space analysis to provide qualitative insights about the behavior of the optimal solution.

We consider a natural generalization of the eigenvalue problem for the Laplacian with homogeneous Dirichlet boundary conditions. This corresponds to look for the critical values of the Dirichlet integral, constrained to the unit Lq sphere. We collect some results, present some counter-examples and compile a list of open problems.

The effects of a nonminimally coupled curvature-matter model of gravity on planetary orbits are computed. The parameters of the model are then constrained by the observation of Mercury orbit.

The existence of eigenfunctions for a class of fully anisotropic elliptic equations is established. The relevant equations are associated with constrained minimization problems for integral func- tionals depending on the gradient of competing functions through general anisotropic Young functions. In particular, the latter need neither be radial, nor have a polynomial growth, and are not even assumed to satisfy the so called \Delta_2-condition. In particular, our analysis requires the development of some new aspects of the theory of anisotropic Orlicz-Sobolev spaces.

A prey-predator system with logistic growth of prey and hunting cooperation of predators is studied. The introduction of fractional time derivatives and the related persistent memory strongly characterize the model behavior, as many dynamical systems in the applied sciences are well described by such fractional-order models. Mathematical analysis and numerical simulations are performed to highlight the characteristics of the proposed model.