Cylindrical gravitational waves: C-energy, super-energy and associated dynamical effects

The energy content of cylindrical gravitational wave spacetimes is analyzed by considering two local descriptions of energy associated with the gravitational field, namely those based on the C-energy and the Bel-Robinson super-energy tensor. A Poynting-Robertson-like effect on the motion of massive test particles, beyond the geodesic approximation, is discussed, allowing them to interact with the background field through an external force which accounts for the exchange of energy and momentum between particles and waves.

Godel spacetime: Planar geodesics and gyroscope precession

Using standard cylindrical-like coordinates naturally adapted to the cylindrical symmetry of the Godel spacetime, we study elliptic like geodesic motion on hyperplanes orthogonal to the symmetry axis through an eccentricity-semi-latus rectum parametrization which is familiar from the Newtonian description of a two-body system. We compute several quantities which summarize the main features of the motion, namely the coordinate time and proper time periods of the radial motion, the frequency of the azimuthal motion, the full variation of the azimuthal angle over a period, and so on.

Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis

To investigate the effects of Glatiramer Acetate (GA) on B cells by an integrated computational and experimental approach. GA is an immunomodulatory drug approved for the treatment of multiple sclerosis (MS). GA effect on B cells is yet to be fully elucidated. We compared transcriptional profiles of B cells from treatment-naive relapsing remitting MS patients, treated or not with GA for 6 hours in vitro, and of B cells before and after six months of GA administration in vivo.

Edge Computing Perspectives: Architectures, Technologies, and Open Security Issues

Edge and Fog Computing will be increasingly pervasive in the years to come due to the benefits they bring in many specific use-case scenarios over traditional Cloud Computing. Nevertheless, the security concerns Fog and Edge Computing bring in have not been fully considered and addressed so far, especially when considering the underlying technologies (e.g. virtualization) instrumental to reap the benefits of the adoption of the Edge paradigm. In particular, these virtualization technologies (i.e.

The sparse method of simulated quantiles: An application to portfolio optimization

The sparse multivariate method of simulated quantiles (S-MMSQ) is applied to solve a portfolio optimization problem under value-at-risk constraints where the joint returns follow a multivariate skew-elliptical stable distribution. The S-MMSQ is a simulation-based method that is particularly useful for making parametric inference in some pathological situations where the maximum likelihood estimator is difficult to compute.

Scattering of uncharged particles in the field of two extremely charged black holes

We investigate the motion of uncharged particles scattered by a binary system consisting of extremely charged black holes in equilibrium as described by the Majumdar-Papapetrou solution. We focus on unbound orbits confined to the plane containing both black holes. We consider the two complementary situations of particles approaching the system along a direction parallel to the axis where the black holes are displaced and orthogonal to it.

Black hole geodesic parallel transport and the Marck reduction procedure

The Wigner rotations arising from the combination of boosts along two different directions arc rederived from a relative boost point of view and applied to study gyroscope spin precession along timelike geodesics in a Kerr spacetime. First this helps to clarify the geometrical properties of Marck's recipe for reducing the equations of parallel transport along such world lines expressed in terms of the constants of the motion to a single differential equation for the essential planar rotation.

Nonlinear-in-spin effects in effective-one-body waveform models of spin-aligned, inspiralling, neutron star binaries

Spinning neutron stars acquire a quadrupole moment due to their own rotation. This quadratic-in-spin, self-spin effect depends on the equation of state (EOS) and affects the orbital motion and rate of inspiral of neutron star binaries. Building upon circularized post-Newtonian results, we incorporate the EOS-dependent self-spin (or monopole-quadrupole) terms in the spin-aligned effective-one-body (EOB) waveform model TEOBResumS at next-to-next-to-leading (NNLO) order, together with other (bilinear, cubic and quartic) nonlinear-in-spin effects (at leading order, LO).

Hypoxia-regulated miRNAs in human mesenchymal stem cells: Exploring the regulatory effects in ischemic disorders

Human mesenchymal/stromal stem cells (hMSC) are the most promising cell source for adult cell therapies in regenerative medicine. Many clinical trials have reported the use of autologous transplantation of hMSCs in several disorders, but with limited results. To exert their potential, hMSCs could exhibit efficient homing and migration toward lesion sites among other effects, but the underlying process is not clear enough. To further increase the knowledge, we studied the co-regulation between hypoxia-regulated genes and miRNAs.

Panic, Irrationality, and Herding: Three Ambiguous Terms in Crowd Dynamics Research

Background. The three terms "panic", "irrationality", and "herding" are ubiquitous in the crowd dynamics literature and have a strong influence on both modelling and management practices. The terms are also commonly shared between the scientific and nonscientific domains. The pervasiveness of the use of these terms is to the point where their underlying assumptions have often been treated as common knowledge by both experts and lay persons. Yet, at the same time, the literature on crowd dynamics presents ample debate, contradiction, and inconsistency on these topics. Method.