Advancements in RNASeqGUI towards a Reproducible Analysis of RNA-Seq Experiments

We present the advancements and novelties recently introduced in RNASeqGUI, a graphical user interface that helps biologists to handle and analyse large data collected in RNA-Seq experiments. This work focuses on the concept of reproducible research and shows how it has been incorporated in RNASeqGUI to provide reproducible (computational) results. The novel version of RNASeqGUI combines graphical interfaces with tools for reproducible research, such as literate statistical programming, human readable report, parallel executions, caching, and interactive and web-explorable tables of results.

Advantages and limits in the adoption of reproducible research and R-tools for the analysis of omic data

Reproducible (computational) Research is crucial to produce transparent and high quality scientific papers. First, we illustrate the benefits that scientific community can receive from the adoption of Reproducible Research standards in the analysis of high-throughput omic data. Then, we describe several tools useful to researchers to increase the reproducibility of their works. Moreover, we face the advantages and limits of reproducible research and how they could be addressed and solved.

Filtered integration rules for finite weighted Hilbert transforms

A product quadrature rule, based on the filtered de la Vallée Poussin polynomial approximation, is proposed for evaluating the finite weighted Hilbert transform in [-1,1]. Convergence results are stated in weighted uniform norm for functions belonging to suitable Besov type subspaces. Several numerical tests are provided, also comparing the rule with other formulas known in literature.

Numerical simulation of a multi-group age-of-infection model

Age of infection epidemic models [1, 3], based on non-linear integro-dierential equations, naturally describe the evolution of diseases whose infectivity depends on the time since becoming infected. Here we consider a multi-group age of infection model [2] and we extend the investigations in [4], [5] and [6] to provide numerical solutions that retain the main properties of the continuous system. In particular, we use Direct Quadrature methods and prove that the numerical solution is positive and bounded.

Towards EXtreme scale technologies and accelerators for euROhpc hw/Sw supercomputing applications for exascale: The TEXTAROSSA approach

In the near future, Exascale systems will need to bridge three technology gaps to achieve high performance while remaining under tight power constraints: energy efficiency and thermal control; extreme computation efficiency via HW acceleration and new arithmetic; methods and tools for seamless integration of reconfigurable accelerators in heterogeneous HPC multi-node platforms. TEXTAROSSA addresses these gaps through a co-design approach to heterogeneous HPC solutions, supported by the integration and extension of HW and SW IPs, programming models, and tools derived from European research.

EULER EQUATIONS AND TRACE PROPERTIES OF MINIMIZERS OF A FUNCTIONAL FOR MOTION COMPENSATED INPAINTING

We compute the Euler equations of a functional useful for simultaneous video inpainting and motion estimation, which was obtained in [17] as the relaxation of a modified version of the functional proposed in [16]. The functional is defined on vectorial functions of bounded variations, therefore we also get the Euler equations holding on the singular sets of minimizers, highlighting in particular the conditions on the jump sets.

Lagrange-Chebyshev Interpolation for image resizing

Image resizing is a basic tool in image processing, and in literature, we have many methods based on different approaches, which are often specialized in only upscaling or downscaling. In this paper, independently of the (reduced or enlarged) size we aim to get, we approach the problem at a continuous scale where the underlying function representing the image is globally approximated by its Lagrange-Chebyshev I kind interpolation polynomial corresponding to suitable (tensor product) grids of first kind Chebyshev zeros.