Mass currents in astrophysics generate gravitomagnetic fields of enormous complexity. Gravitomagnetic helicity, in direct analogy with magnetic helicity, is a measure of entwining of the gravitomagnetic field lines. We discuss gravitomagnetic helicity within the gravitoelectromagnetic (GEM) framework of linearized general relativity. Furthermore, we employ the spacetime curvature approach to GEM in order to determine the gravitomagnetic helicity for static observers in Kerr spacetime.

Amino acids (AAs) are well known to be involved in the regulation of glucose metabolism and, in particular, of insulin secretion. However, the effects of different AAs on insulin release and kinetics have not been completely elucidated. The aim of this study was to propose a mathematical model that includes the effect of AAs on insulin kinetics during a mixed meal tolerance test. To this aim, five different models were proposed and compared.

Gravitational radiation can be decomposed as an infinite sum of radiative multipole moments, which parametrize the waveform at infinity. The multipolar-post-Minkowskian formalism provides a connection between these multipoles and the source multipole moments, known as explicit integrals over the matter source. The gravitational wave energy, angular momentum, and linear momentum fluxes are then expressed as multipolar expansions containing certain combinations of the source moments.

FORUM (Far-infrared Outgoing Radiation Understanding and Monitoring) is a Fourier Transform Spectrometer (FTS) that will fly as the 9th ESA's Earth Explorer mission. FORUM will sound the atmosphere in the 100-1600 cm-1 region, covering the Far Infrared (FIR) and part of the Middle Infrared (MIR), accounting for more than 95% of the outgoing longwave flux lost by our planet. We review the constrains for the emissivity retrieval.

Drug delivery carriers are considered an encouraging approach for the localized treatment of disease with minimum effect on the surrounding tissue. Particularly, layer-by-layer releasing particles have gained increasing interest for their ability to develop multifunctional systems able to control the release of one or more therapeutical drugs and biomolecules. Although experimental methods can offer the opportunity to establish cause and effect relationships, the data collection can be excessively expensive or/and time-consuming.

We study some properties of a nonconvex variational problem. The infimum of the functional that has to be minimized fails to be attained. Instead, minimizing sequences develop gradient oscillations which allow them to decrease the value of the functional. We show an existence result for a perturbed nonconvex version of the problem, and we study the qualitative properties of the corresponding minimizer. The pattern of the gradient oscillations for the original non perturbed problem is analyzed numerically.

Multiple emulsions are a class of soft fluid in which small drops are immersed within a larger one and stabilized over long periods of time by a surfactant. We recently showed that, if a monodisperse multiple emulsion is subject to a pressure-driven flow, a wide variety of nonequilibrium steady states emerges at late times, whose dynamics relies on a complex interplay between hydrodynamic interactions and multibody collisions among internal drops.

We report new dynamical modes in confined soft granular flows, such as stochastic jetting and dripping, with no counterpart in continuum viscous fluids. The new modes emerge as a result of the propagation of the chaotic behavior of individual grains - here, monodisperse emulsion droplets - to the level of the entire system as the emulsion is focused into a narrow orifice by an external viscous flow. We observe avalanching dynamics and the formation of remarkably stable jets - single-file granular chains - which occasionally break, resulting in a non-Gaussian distribution of cluster sizes.

Targeted drug delivery systems represent a promising strategy to treat localised disease with minimum impact on the surrounding tissue. In particular, polymeric nanocontainers have attracted major interest because of their structural and morphological advantages and the variety of polymers that can be used, allowing the synthesis of materials capable of responding to the biochemical alterations of the environment.

Variational methods for image segmentation try to recover a piecewise smooth function together with a discontinuity set which represents the boundaries of the segmentation. This paper deals with a variational method that constrains the formation of discontinuities along smooth contours. The functional to be minimized, which involves the computation of the geometrical properties of the boundaries, is approximated by a sequence of functionals which can be discretized in a straightforward way. Computer examples of real images are presented to illustrate the feasibility of the method.