We present a solution based on a suitable combination of heuristics and parallel processing techniques for finding the best allocation of the financial assets of a pension fund, taking into account all the specific rules of the fund. We compare the values of an objective function computed with respect to a large set (thousands) of possible scenarios for the evolution of the Net Asset Value (NAV) of the share of each asset class in which the financial capital of the fund is invested.

A nullomer is an oligomer that does not occur as a subsequence in a given DNA sequence, i.e. it is an absent word of that sequence. The importance of nullomers in several applications, from drug discovery to forensic practice, is now debated in the literature. Here, we investigated the nature of nullomers, whether their absence in genomes has just a statistical explanation or it is a peculiar feature of genomic sequences. We introduced an extension of the notion of nullomer, namely high order nullomers, which are nullomers whose mutated sequences are still nullomers.

Presentazione a convegno

Many studies have shown that Physarum polycephalum slime mold is able to find the shortest path in a maze. In this paper we study this behavior in a network, using a hyperbolic model of chemotaxis. Suitable transmission and boundary conditions at each node are considered to mimic the behavior of such an organism in the feeding process. Several numerical tests are presented for special network geometries to show the qualitative agreement between our model and the observed behavior of the mold.

HVAC systems are the largest energy consumers in a building and a clean HVAC system can get about 11% in energy saving. Moreover, particulate pollution represents one of the main causes of cancer death and several health damages. This paper presents an innovative and not invasive procedure for the automatic indoor air quality assessment that depends on HVAC cleaning conditions. It is based on a mathematical algorithm that processes a few on-site physical measurements that are acquired by dedicated sensors at suitable locations with a specif-ic time table.

We briefly review some aspects of the anomalous diffusion, and its relevance in reactive systems. In particular we consider strong anomalous diffusion characterized by the moment behaviour <(x(t)(q)> similar to t(qv)(q), where v(q) is a non constant function, and we discuss its consequences. Even in the apparently simple case v(2) = 1/2, strong anomalous diffusion may correspond to non trivial features, such as non Gaussian probability distribution and peculiar scaling of large order moments.

Presentazione a convegno

We give a general Gaussian bound for the first chaos (or innovation) of point processes with stochastic intensity constructed by embedding in a bivariate Poisson process. We apply the general result to nonlinear Hawkes processes, providing quantitative central limit theorems.

Immunosenescence is thought to result from cellular aging and to reflect exposure to environmental stressors and antigens, including cytomegalovirus (CMV). However, not all of the features of immunosenescence are consistent with this view, and this has led to the emergence of the sister theory of "inflammaging". The recently discovered diffuse tissue distribution of resident memory T cells (TRM) which don't recirculate, calls these theories into question. These cells account for most T cells residing in barrier epithelia which sit in and travel through the extracellular matrix (ECM).

We present a computational method for commodity hardware-based clinical cardiovascular diagnosis based on accurate simulation of cardiovascular blood flow. Our approach leverages the flexibility of the Lattice Boltzmann method to implementation on high-performance, commodity hardware, such as Graphical Processing Units. We developed the procedure for the analysis of real-life cardiovascular blood flow case studies, namely, anatomic data acquisition, geometry and mesh generation, flow simulation and data analysis and visualization.