This paper focuses on two-tier city logistics systems for advanced management of urban freight activities and, in particular, on the first layer of such systems where freight is moved from distribution centers on the outskirts of the city to satellite platforms by urban vehicles, from where it will be distributed to customers by a different fleet of dedicated vehicles. We address the issue of planning the services of this first tier system, that is, select services, their routes and schedules, and determine the itineraries of the customer-demand flows through these facilities and services.