Aiming at a quantitative understanding of basic aspects of pedestrian dynamics, extensive and high-accuracy measurements of real-life pedestrian trajectories have been performed. A measurement strategy based on Microsoft KinectTM has been used. Specifically, more than 100.000 pedestrians have been tracked while walking along a trafficked corridor at the Eindhoven University of Technology, The Netherlands.

In this paper we propose a multiperiod optimization model based on the maximal covering location problem in order to support safety policies within urban areas. In particular, we focus on the field of car accidents control, by considering the problem of the optimal location of intersection safety cameras (ISC) on an urban traffic network to maximize road control and reduce the number and the impact of car accidents. The effectiveness of accidents prevention programs can be increased by changing periodically the position of the available ISCs on a given time horizon.

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Motivation: The human immune system evolved a multi-layered control mechanism to eliminate self-reactive cells. Of these so-called tolerance induction mechanisms, lymphocytes T education in the thymus gland represents the very first one. This complicated process is not fully understood and quantitative models able to help in this endeavor are lacking.