In this article we present evidence for a relationship between chromosome gene loci and the topological properties of the protein-protein interaction network corresponding to the set of genes under consideration. Specifically, for each chromosome of the Saccharomyces cerevisiae genome, the distribution of the intra-chromosome inter-gene distances was analyzed and a positive correlation with the distance among the corresponding proteins of the protein-protein interaction network was found.

The aim of this work is to analyze the hydroacoustic behavior of a marine propeller through the acoustic analogy and to test the versatility and effectiveness of this approach in dealing with the many (and relatively unexplored) issues concerning the underwater noise and its numerical prediction. In particular, a propeller in a noncavitating open water condition is examined here by coupling a Reynolds averaged Navier-Stokes hydrodynamic solver to a hydroacoustic code implementing different resolution forms of the Ffowcs Williams-Hawkings (FWH) equation.

In this paper the Acoustic Analogy is used to predict the underwater noise from a complete scaled ship model in a steady course. The numerical investigation is performed by coupling an incompressible RANS code, equipped with a level-set approach to account for the fundamental time evolution of the free surface, to a FWHbased hydroacoustic solver, here suitably designed to manage the huge set of data coming from a full-unsteady hydrodynamic simulation.

The acoustic analogy represents a powerful and versatile approach, able to numerically predict the noise generated by a body moving in a fluid. It is widely used to provide essential indications about the aeroacoustic behavior of aircraft and helicopters (even at a design stage) and, eventually, to pursue effective strategies aimed at desirable reduction and/or control of noise. Nevertheless, applications in the area of hydroacoustics and in the prediction of ship underwater noise are very rare.

An algorithm for computing the solution of indefinite least squares problems and of indefinite least squares problems with equality constrained is presented. Such problems arise when solving total least squares problems and in H infinity-smoothing. The proposed algorithm relies only on stable orthogonal transformations reducing recursively the associated augmented matrix to proper block anti-triangular form. Some numerical results are reported showing the properties of the algorithm.