Joining RDC data from flexible protein domains
We study the inverse problem of determining the conformational freedom of
two protein domains from residual dipolar coupling (RDC) measurements. For
each paramagnetic ion attached to one of the domains we obtain a magnetic
susceptibility tensor ? from the RDC of couples of atoms of that domain,
and a mean paramagnetic susceptibility tensor ?¯ from the RDC of couples
of atoms of the other domain. The latter is an integral average of rotations
of ? which depends on the conformational freedom of the two domains.






