We present a general model of drug release from a drug delivery device and the subsequent transport in biological tissue. The model incorporates drug diffusion, dissolution and solubility in the polymer coating, coupled with diffusion, convection and reaction in the biological tissue. Each layer contains bound and free drug phases so that the resulting model is a coupled two-phase two-layer system of partial differential equations. One of the novelties is the generality of the model in each layer.

Motivated by the observation that electrons in graphene, in the hydrodynamic regime of transport, can be treated as a two-dimensional ultrarelativistic gas with very low shear viscosity, we examine the existence of the Rayleigh-Bénard instability in a massless electron-hole plasma. First, we perform a linear stability analysis, derive the leading contributions to the relativistic Rayleigh number, and calculate the critical value above which the instability develops.

In this work a Discrete Boltzmann Model for the solution of transcritical 2D shallow water flows is presented and validated. In order to provide the model with transcritical capabilities, a particular multispeed velocity set has been employed for the discretization of the Boltzmann equation. It is shown that this particular set naturally yields a simple and closed procedure to determine higher order equilibrium distribution functions needed to simulate transcritical flow.

One of the most popular discrete approximating polynomials is the Lagrange interpolation polynomial and the Jacobi zeros provide a particularly convenient choice of the interpolation knots on [?1, 1]. However, it is well known that there is no point system such that the associate sequence of Lagrange polynomials, interpolating an arbitrary function f, would converge to f w.r.t. any weighted uniform or L1 norm.

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A discrete Boltzmann model (DBM) is developed to investigate the hydrodynamic and thermodynamic non-equilibrium (TNE) effects in phase separation processes. The interparticle force drives changes and the gradient force, induced by gradients of macroscopic quantities, opposes them. In this paper, we investigate the interplay between them by providing a detailed inspection of various non-equilibrium observables. Based on the TNE features, we define TNE strength which roughly estimates the deviation amplitude from the thermodynamic equilibrium.

Plastic rearrangements play a crucial role in the characterization of soft-glassy materials, such as emulsions and foams. Based on numerical simulations of soft-glassy systems, we study the dynamics of plastic rearrangements at the hydrodynamic scales where thermal fluctuations can be neglected.

Gaussian quadrature has been extensively studied in literature and several error estimates have been proved under dierent smoothness assumptions of the integrand function. In this talk we are going to state a general error estimate for Gauss-Jacobi quadrature, based on the weighted moduli of smoothness introduced by Z. Ditzian and V. Totik in [1]. Such estimate improves a previous result in [1, Theorem 7.4.1] and it includes several error bounds from literature as particular cases.

In the present work the simulation of water impacts is discussed. The investigation is mainly focused on the energy dissipation involved in liquid impacts in both the frameworks of the weakly compressible and incompressible models. A detailed analysis is performed using a weakly compressible Smoothed Particle Hydrodynamics (SPH) solver and the results are compared with the solutions computed by an incompressible mesh-based Level-Set Finite Volume Method (LS-FVM). Impacts are numerically studied using single-phase models through prototypical problems in 1D and 2D frameworks.