A 1D mechanistic model can predict duration of in-vivo drug release from drug-eluting stents

We present a general model of drug release from a drug delivery device and the subsequent transport in biological tissue. The model incorporates drug diffusion, dissolution and solubility in the polymer coating, coupled with diffusion, convection and reaction in the biological tissue. Each layer contains bound and free drug phases so that the resulting model is a coupled two-phase two-layer system of partial differential equations. One of the novelties is the generality of the model in each layer.

Subsoil decontamination with bioventing: numerical experiments

A mathematical model describing the bioventing technique for the decontamination of pol- luted subsoil will be presented. Bioventing is a biological technique: bacteria remove the contaminant transforming it and oxygen is consumed in the reaction. The numerical model is based on the fluid flow theory in porous media and bacteria population dynamics and it describes: pollutant degradation, oxygen and bacteria concentration. The mathematical model will be numerically solved and the results of some experiments will be presented.

Effect of an arbitrary spin orientation on the quadrupolar structure of an extended body in a Schwarzschild spacetime

The influence of an arbitrary spin orientation on the quadrupolar structure of an extended body moving in a Schwarzschild spacetime is investigated. The body dynamics is described by the Mathisson-Papapetrou-Dixon model, without any restriction on the motion or simplifying assumption on the associated spin vector and quadrupole tensor, generalizing previous works.

Least Recently Used Caches Under the Shot Noise Model

In this paper we develop an analytical framework, based on Che's approximation [2], for the analysis of Least Recently Used (LRU) caches operating under the Shot Noise requests Model (SNM). The SNM was recently proposed in [12] to better capture the main characteristics of today Video on Demand (Vod) traffic. In this context, Che's approximation is derived as the application of a mean field principle to the cache eviction time. We investigate the validity of this approximation through an asymptotic analysis of the cache eviction time.