Muscl reconstruction and haar wavelets

MUSCL extensions (Monotone Upstream-centered Schemes for Conservation Laws) of the Godunov numerical scheme for scalar conservation laws are shown to admit a rather simple reformulation when recast in the formalism of the Haar multi-resolution analysis of L<sup>2</sup>(R). By pursuing this wavelet reformulation, a seemingly new MUSCL-WB scheme is derived for advection-reaction equations which is stable for a Courant number up to 1 (instead of roughly 1/2 ).

On the model inconsistencies in simulating breaking wave with mesh-based and particle methods

In the present work the numerical simulation of breaking wave processes is discussed. A detailed analysis is performed using Smoothing Particle Hydrodynamics (SPH) models as well as a mesh-based Level-Set Finite Volume Method (LS-FVM). Considerations on the numerical dissipation involved in such models are discussed within the frameworks of weakly compressible and incompressible ssumptions. The breaking wave processes are simulated using both mono- and two-phases models. Due to the extensive test-cases discussed, the present analysis is limited to a bi-dimensional framework.

Prediction of energy losses in water impacts using incompressible and weakly compressible models

In the present work the simulation of water impacts is discussed. The investigation is mainly focused on the energy dissipation involved in liquid impacts in both the frameworks of the weakly compressible and incompressible models. A detailed analysis is performed using a weakly compressible Smoothed Particle Hydrodynamics (SPH) solver and the results are compared with the solutions computed by an incompressible mesh-based Level-Set Finite Volume Method (LS-FVM). Impacts are numerically studied using single-phase models through prototypical problems in 1D and 2D frameworks.

Numerical simulations of aggregate breakup in bounded and unbounded turbulent flows

Breakup of small aggregates in fully developed turbulence is studied by means of direct numerical simulations in a series of typical bounded and unbounded flow configurations, such as a turbulent channel flow, a developing boundary layer and homogeneous isotropic turbulence. The simplest criterion for breakup is adopted, whereby aggregate breakup occurs when the local hydrodynamic stress "1=2, with " being the energy dissipation at the position of the aggregate, overcomes a given threshold cr, which is characteristic for a given type of aggregate.

Chronology protection in the Kerr metric

We show that causality violation in a Kerr naked singularity spacetime is constrained by the existence of (radial) potential barriers. We extend to the class of vortical non-equatorial null geodesics confined to $$\theta $$? $$=$$= constant hyperboloids (boreal orbits) previous results concerning timelike ones (Calvani et al. in Gen Rel Gravit 9:155, 1978), showing that within this class of orbits, the causality principle is rigorously satisfied.

Massless Dirac particles in the vacuum C-metric

We study the behavior of massless Dirac particles in the vacuum C-metric spacetime, representing the nonlinear superposition of the Schwarzschild black hole solution and the Rindler flat spacetime associated with uniformly accelerated observers. Under certain conditions, the C-metric can be considered as a unique laboratory to test the coupling between intrinsic properties of particles and fields with the background acceleration in the full (exact) strong-field regime.

Immune System Modeling and Simulations

This book describes a computational model of the immune system reaction, C-ImmSim. The book presents the basic model as well as the various customizations to implement the description of different diseases and the way they have been used to produce new knowledge either from hypothesis or from experimental data. The book can be used as a practical guide to implement a computational model with which to study a specific disease and to try to address realistic clinical questions.

Algorithm for the numerical assessment of the conjecture of a subglacial lake at Svalbard, Spitzbergen

The melting of glaciers coming with climate change threatens the heritage of the last glaciation of Europe likely contained in subglacial lakes in Greenland and Svalbard. This aspect urges specialists to focus their studies (theoretical, numerical and on-field) on such fascinating objects. Along this line we have built up a numerical procedure for validating the conjecture of the existence of a subglacial lake beneath the Amundsenisen Plateau at South-Spitzbergen, Svalbard. In this work we describe the algorithm and significant representative results of the related numerical test.

Locally inertial approximations of balance laws arising in (1 + 1)-dimensional general relativity

An elementary model of (1 + 1)-dimensional general relativity, known as "R = T " and mainly developed by Mann and coworkers in the early 1990s, is set up in various contexts. Its formulation, mostly in isothermal coordinates, is derived and a relativistic Euler system of selfgravitating gas coupled to a Liouville equation for the metric's conformal factor is deduced.

ZFP57 recognizes multiple and closely spaced sequence motif variants to maintain repressive epigenetic marks in mouse embryonic stem cells.

Imprinting Control Regions (ICRs) need to maintain their parental allele-specific DNA methylation during early embryogenesis despite genome-wide demethylation and subsequent de novo methylation. ZFP57 and KAP1 are both required for maintaining the repressive DNA methylation and H3-lysine-9-trimethylation (H3K9me3) at ICRs. In vitro, ZFP57 binds a specific hexanucleotide motif that is enriched at its genomic binding sites.