Applications of network-based survival analysis methods for pathway detection in cancer

Gene expression data from high-throughput assays, such as microarray, are often used to predict cancer survival. Available datasets consist of a small number of samples (n patients) and a large number of genes (p predictors). Therefore, the main challenge is to cope with the high-dimensionality. Moreover, genes are co-regulated and their expression levels are expected to be highly correlated. In order to face these two issues, network based approaches can be applied.

Numerical solution of the Perspective Shape- from-Shading problem

We study the Perspective Shape from Shading problem from the numerical point of view pre- senting a simple algorithm to compute its solution. The scheme is based on a semi-Lagrangian approximation of the first order Hamilton-Jacobi equation related to the problem. The scheme is converging to the weak solution (in the viscosity sense) of the equation and allows to compute accurately regular as well as non regular solutions.

Global existence and asymptotic stability of smooth solutions to a fluid dynamics model of biofilms in one space dimension

In this paper, we present an analytical study, in the one space dimensional case, of the fluid dynamics system proposed in [3] to model the formation of biofilms. After showing the hyperbolicity of the system, we show that, in an open neighborhood of the physical parameters, the system is totally dissipative near its unique non-vanishing equilibrium point.

CFD Maneuvering Prediction of a Twin Screw Vessel with Different Stern Appendages Configuration

The turning circle maneuver of a self-propelled tanker like ship model is numerically simulated through the integration of the unsteady Reynolds averaged Navier-Stokes (uRaNS) equations coupled with the equations of the motion of a rigid body. The solution is achieved by means of the unsteady RANS solver ?navis developed at CNR-INSEAN. The focus here is on the analysis of the maneuvering behavior of the ship with two different stern appendages configurations; namely, a twin screw with a single rudder and a twin screw, twin rudder with a central skeg.

A non-local rare mutations model for quasispecies and prisoner's dilemma: Numerical assessment of qualitative behaviour

An integro-differential model for evolutionary dynamics with mutations is investigated by improving the understanding of its behaviour using numerical simulations. The proposed numerical approach can handle also density dependent fitness, and gives new insights about the role of mutation in the preservation of cooperation.

On a continuous mixed strategies model for Evolutionary game theory

We consider an integro-differential model for evolutionary gametheory which describes the evolution of a population adopting mixed strategies.Using a reformulation based on the first moments of the solution, we provesome analytical properties of the model and global estimates. The asymptoticbehavior and the stability of solutions in the case of two strategies is analyzedin details. Numerical schemes for two and three strategies which are able tocapture the correct equilibrium states are also proposed together with severalnumerical examples. © American Institute of Mathematical Sciences.

A destination-preserving model for simulating Wardrop equilibria in traffic flow on networks

In this paper we propose a LWR-like model for traffic flow on networks which allows to track several groups of drivers, each of them being characterized only by their destination in the network. The path actually followed to reach the destination is not assigned a priori, and can be chosen by the drivers during the journey, taking decisions at junctions. The model is then used to describe three possible behaviors of drivers, as- sociated to three different ways to solve the route choice problem: 1. Drivers ignore the presence of the other vehicles; 2.

Comparison of SAR amplitude vs. coherence flood detection methods - A GIS application

Flood area detection from multipass Synthetic Aperture Radar (SAR) data can be performed via amplitude change detection techniques. These methods allow flooded zones to be discriminated only when they are flooded at the time of the second passage, and not at the time of the first one. Coherence derived from multipass SAR interferometry can be used instead, as an indicator of changes in the electromagnetic scattering behaviour of the surface, thus potentially revealing all the areas affected by the flood event at any time between the two passes.