Applications of network-based survival analysis methods for pathway detection in cancer
Gene expression data from high-throughput assays, such as
microarray, are often used to predict cancer survival. Available datasets
consist of a small number of samples (n patients) and a large number of
genes (p predictors). Therefore, the main challenge is to cope with the
high-dimensionality. Moreover, genes are co-regulated and their expression
levels are expected to be highly correlated. In order to face these
two issues, network based approaches can be applied.






