Multidimensional extensions of the Bernoulli and Appell polynomials are defined generalizing the corresponding generating functions, and using the Hermite-Kampe de Feriet (or Gould-Hopper) polynomials. Furthermore the differential equations satisfied by the corresponding 2D polynomials are derived exploiting the factorization method, introduced in [15].

We present a multiphase mathematical model for tumor growth which incorporates the remodeling of the extracellular matrix and describes the formation of fibrotic tissue by tumor cells. We also detail a full qualitative analysis of the spatially homogeneous problem, and study the equilibria of the system in order to characterize the conditions under which fibrosis may occur. © 2010 Elsevier Ltd.

The Hilbert transform of a function g, H(g) is an important tool in many mathematical fields. Expecially its numerical evaluation is often useful in some procedures for searcing solutions of the singular integral equations. In this context an approximation of (HV^alpha,beta,f;t), |t|1, where f is a continuous function in [-1,1] and v^alpha,beta, alpha,beta>-1 is a Jacobi weight, is required. In the last decade more then one paper appeared on this subject and among others we recall [1,2,3,4,5,14,15,20]. The procedure used in these papers can be described as follows.

Collocation and quadrature methods for Cauchy singular integral equations on an interval with variable coefficients are studied. Convergence rates are proved in weighted uniform and uniform norms.

In this work the phenomenon of contact inhibition of growth is studied by applying an individual based model and a continuum multiphase model to describe cell colony growth in vitro. The impact of different cell behavior in response to mechanical cues is investigated. The work aims at comparing the results from both models from the qualitative and, whenever possible, also the quantitative point of view. Crown Copyright © 2009.