Statistical properties of thermally expandable particles in soft-turbulence Rayleigh-Bénard convection

The dynamics of inertial particles in Rayleigh-Benard convection, where both particles and fluid exhibit thermal expansion, is studied using direct numerical simulations (DNS) in the soft-turbulence regime. We consider the effect of particles with a thermal expansion coefficient larger than that of the fluid, causing particles to become lighter than the fluid near the hot bottom plate and heavier than the fluid near the cold top plate.

Measure-valued solutions to a nonlinear fourth-order regularization of forward-backward parabolic equations

We introduce and analyze a new, nonlinear fourth-order regularization of forwardbackward parabolic equations. In one space dimension, under general assumptions on the potentials, which include those of Perona-Malik type, we prove existence of Radon measure-valued solutions under both natural and essential boundary conditions.

Numerical optimization of plasmid DNA delivery combined with hyaluronidase injection for electroporation protocol

Background and Objective: The paper focuses on the numerical strategies to optimize a plasmid DNA delivery protocol, which combines hyaluronidase and electroporation. Methods: A well-defined continuum mechanics model of muscle porosity and advanced numerical optimization strategies have been used, to propose a substantial improvement of a pre-existing experimental protocol of DNA transfer in mice. Our work suggests that a computational model might help in the definition of innovative therapeutic procedures, thanks to the fine tuning of all the involved experimental steps.

ALIASING AND TWO-DIMENSIONAL WELL-BALANCED FOR DRIFT-DIFFUSION EQUATIONS ON SQUARE GRIDS

A notion of "2D well-balanced" for drift-diffusion is proposed. Exactness at steady-state, typical in 1D, is weakened by aliasing errors when deriving "truly 2D" numerical fluxes from local Green's function. A main ingredient for proving that such a property holds is the optimality of the trapezoidal rule for periodic functions. In accordance with practical evidence, a "Bessel scheme" previously introduced in [SIAM J. Numer. Anal. 56 (2018), pp. 2845-2870] is shown to be "2D well-balanced" (along with former algorithms known as "discrete weighted means" or "tailored schemes".