Spectral emissivity is a key property of the Earth surface of which only very few measurements exist so far in the far-infrared (FIR) spectral region, even though recent work has shown its FIR contribution is important for accurate modelling of global climate. The European Space Agency's 9th Earth Explorer, FORUM (Far-infrared Outgoing Radiation Understanding and Monitoring) will provide the first global spectrally resolved measurements of the Earth's top-of-the-atmosphere (TOA) spectrum in the FIR.

The observations acquired during the full mission of the Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) instrument, aboard the European Space Agency Environmental Satellite (Envisat), have been analysed with version 8.22 of the Optimised Retrieval Model (ORM), originally developed as the scientific prototype of the ESA level-2 processor for MIPAS observations.

Identifying relevant genomic features that can act as prognostic markers for building predictive survival models is one of the central themes in medical research, affecting the future of personalized medicine and omics technologies. However, the high dimension of genome-wide omic data, the strong correlation among the features, and the low sample size significantly increase the complexity of cancer survival analysis, demanding the development of specific statistical methods and software.

The feasibility of liver transplantation from old healthy donors suggests that this organ is able to preserve its functionality during aging. To explore the biological basis of this phenomenon, we characterized the epigenetic profile of liver biopsies collected from 45 healthy liver donors ranging from 13 to 90 years old using the Infinium HumanMethylation450 BeadChip. The analysis indicates that a large remodeling in DNA methylation patterns occurs, with 8823 age-associated differentially methylated CpG probes.

In Alicandro et al. (J Mech Phys Solids 92:87-104, 2016) a simple discrete scheme for the motion of screw dislocations toward low energy configurations has been proposed. There, a formal limit of such a scheme, as the lattice spacing and the time step tend to zero, has been described. The limiting dynamics agrees with the maximal dissipation criterion introduced in Cermelli and Gurtin (Arch Ration Mech Anal 148, 1999) and predicts motion along the glide directions of the crystal.

Conformational variability and heterogeneity are crucial determinants of the function of biological macromolecules. The possibility of accessing this information experimentally suffers from severe under-determination of the problem, since there are a few experimental observables to be accounted for by a (potentially) infinite number of available conformational states. Several computational methods have been proposed over the years in order to circumvent this theoretically insurmountable obstacle.

The present study assesses the viability of including water vapor data from Interferometry Synthetic Aperture Radar (InSAR) in the initialization of numerical weather prediction (NWP) models, using already available Sentinel-1 A and B products. Despite the limitations resulting from the 6-day return period of images produced by the 2-satellite system, it is found that for a sufficiently large domain designed to contain a set of images every 12 h (at varying locations), the impact on model performance is beneficial or at least neutral.

We introduce a notion of uniform convergence for local and nonlocal curvatures. Then, we propose an abstract method to prove the convergence of the corresponding geometric flows, within the level set formulation.

We present mesoscale numerical simulations of Rayleigh-Bénard (RB) convection in a two-dimensional model emulsion. The systems under study are constituted of finite-size droplets, whose concentration is systematically varied from small (Newtonian emulsions) to large values (non-Newtonian emulsions). We focus on the characterisation of the heat transfer properties close to the transition from conductive to convective states, where it is well known that a homogeneous Newtonian system exhibits a steady flow and a time-independent heat flux.

In this paper, we use the Z-control approach to get further insight on the role of awareness in the management of epidemics that, just like Covid-19, display a high rate of overexposure because of the large number of asymptomatic people. We focus on a SEIR model including a overexposure mechanism and consider awareness as a time-dependent variable whose dynamics is not assigned a priori.