An introduction to next generation sequencing for studying omic-environment interactions.
In this talk, first, we review the concept of gene-environmental interaction
on the light of emerging results and the use of modern high-throughput technologies;
we illustrate its impact on the understanding of complex human diseases. Then,
we provide an overview of the methods available to process NGS data with particular
emphasis to the detection of genomic variants, the analysis of epigenomic and
transcriptional data produced by modern sequencers. Finally, we discuss how multiomic
data can be used to improve our way of studying complex diseases and can
provide novel research perspectives.