Risk assessment of atherosclerotic plaques based on global biomechanics

We present the results of a computational study of the entire left coronary system simulated both at Newtonian level and at red blood cell resolution for a sizeable number of physiological conditions. We analyze the cardiovascular implications of stenotic plaques and show that the standard clinical criterion for surgical or percutaneous intervention, based on the fractional flow reserve (FFR), is significantly affected by system-dependent, local hemodynamic factors.

Turning ability analysis of a fully appended twin screw vessel by CFD. Part II: Single vs. twin rudder configuration

In the present paper, the analysis of the turning capability of the naval supply vessel presented in Part I (Broglia et al., 2015) is continued with different stern appendages, namely twin rudder and centreline skeg. The main purpose of the analysis is to assess the capability of an in-house CFD tool in capturing the different manoeuvring characteristics of the ship hulls; the test case is challenging, as the difference be- tween the two configurations lies in the complex flow structure related to rudder-propeller interactions. Moreover, although the twin rudder solution slightly improves the

Coupling weakly-compressible SPH with Finite Volume Method: an algorithm for simulating free-surface flows

An algorithm for coupling a classical Finite Volume (FV) approach, that discretize the Navier-Stokes equations on a block structured Eulerian grid, with the weakly-compressible SPH is presented. The coupling procedure aims at applying each solver in the region where its intrinsic characteristics can be exploited in the most efficient and accurate way: the FV solver is used to resolve the bulk flow and the wall regions, whereas the SPH solver is implemented in the free surface region to capture details of the front evolution.

Analysis of free-surface flows through energy considerations: Single-phase versus two-phase modeling

The study of energetic free-surface flows is challenging because of the large range of interface scales involved due to multiple fragmentations and reconnections of the air-water interface with the formation of drops and bubbles. Because of their complexity the investigation of such phenomena through numerical simulation largely increased during recent years. Actually, in the last decades different numerical models have been developed to study these flows, especially in the context of particle methods.

Numerical validation of the conjecture of a subglacial lake at Amundsenisen, Svalbard

The likelihood of a subglacial lake beneath Amundsenisen Plateau at Southern Spitzbergen, Svalbard, pointed out by the flat signal within the Ground Penetrating Radar (GPR) remote survey of the area, is justified, here, via numerical simulation.This investigation has been developed under the assumption that the icefield thickness does not change on average, as it is confirmed by recently published physical measurements taken over the past 40 years.

Dynamics and rheology of cells and vesicles in shear flow

A deep understanding of the dynamics and rheology of suspensions of vesicles, cells, and capsules is relevant for different applications, ranging from soft glasses to blood flow [1]. I will present the study of suspensions of fluid vesicles by a combination of molecular dynamics and mesoscale hydrodynamics simulations (multi-particle collision dynamics) in two dimensions [2], pointing out the big potential of the numerical method to address problems in soft matter.

Robust Design Optimization for the refit of a cargo ship using real seagoing data

Robust Design Optimization (RDO) represents a really interesting opportunity when the specifications of the design are careful and accurate: the possibility to optimize an industrial object for the real usage situation, improving the overall performances while reducing the risk of occurrence of off-design con- ditions, strictly depends on the availability of the information about the probability of occurrence of the various operative conditions during the lifetime of the design.

Long-range hydrodynamic effect due to a single vesicle in linear flow

Vesicles are involved in a vast variety of transport processes in living organisms. Additionally, they serve as a model for the dynamics of cell suspensions. Predicting the rheological properties of their suspensions is still an open question, as even the interaction of pairs is yet to be fully understood. Here we analyse the effect of a single vesicle, undergoing tank-treading motion, on its surrounding shear flow by studying the induced disturbance field delta(V) over right arrow, the difference between the velocity field in its presence and absence.

Experimental and computational investigation of the group 11-group 2 diatomic molecules: First determination of the AuSr and AuBa bond energies and thermodynamic stability of the copper- and silver-alkaline earth species

The dissociation energies of the intermetallic molecules AuSr and AuBa were for the first time determined by the Knudsen effusion mass spectrometry method. The two species were produced in the vapor phase equilibrated with apt mixtures of the constituent elements, and the dissociation equilibria were monitored mass-spectrometrically in the temperature range 1406-1971 K (AuSr) and 1505-1971 K (AuBa).