The core-radius approach to supercritical fractional perimeters, curvatures and geometric flows

We consider a core-radius approach to nonlocal perimeters governed by isotropic kernels having critical and supercritical exponents, extending the nowadays classical notion of s-fractional perimeter, defined for 0<s<1, to the case s>=1. We show that, as the core-radius vanishes, such core-radius regularized s-fractional perimeters, suitably scaled, ?-converge to the standard Euclidean perimeter.

A non-standard numerical scheme for an age-of-infection epidemic model

We propose a numerical method for approximating integro-differential equations arising in age-of-infection epidemic models. The method is based on a non-standard finite differences approximation of the integral term appearing in the equation. The study of convergence properties and the analysis of the qualitative behavior of the numerical solution show that it preserves all the basic properties of the continuous model with no restrictive conditions on the step-length h of integration and that it recovers the continuous dynamic as h tends to zero.

Theoretical model for diffusion-reaction based drug delivery from a multilayer spherical capsule

Controlled drug delivery from a multilayer spherical capsule is used for several therapeutic applications. Developing a theoretical understanding of mass transfer in the multilayer capsule is critical for understanding and optimizing targeted drug delivery. This paper presents an analytical solution for the mass transport problem in a general multilayer sphere involving diffusion as well as drug immobilization in various layers due to binding reactions.

Nonlinear-in-spin effects in effective-one-body waveform models of spin-aligned, inspiralling, neutron star binaries

Spinning neutron stars acquire a quadrupole moment due to their own rotation. This quadratic-in-spin, self-spin effect depends on the equation of state (EOS) and affects the orbital motion and rate of inspiral of neutron star binaries. Building upon circularized post-Newtonian results, we incorporate the EOS-dependent self-spin (or monopole-quadrupole) terms in the spin-aligned effective-one-body (EOB) waveform model TEOBResumS at next-to-next-to-leading (NNLO) order, together with other (bilinear, cubic and quartic) nonlinear-in-spin effects (at leading order, LO).

Network Clustering by Embedding of Attribute-augmented Graphs

In this paper we propose a new approach to detect clusters in undirected graphs with attributed vertices. The aim is to group vertices which are similar not only in terms of structural connectivity but also in terms of attribute values. We incorporate structural and attribute similarities between the vertices in an augmented graph by creating additional vertices and edges as proposed in [6, 38]. The augmented graph is then embedded in a Euclidean space associated to its Laplacian where a modified K-means algorithm is applied to identify clusters.

Jarzynski on work and free energy relations: The case of variable volume

Derivations of the Jarzynski equality (JE) appear to be quite general, and applicable to any particle system, whether deterministic or stochastic, under equally general perturbations of an initial equilibrium state at given temperatureT. At the same time, the definitions of the quantities appearing in the JE, in particular the work, have been questioned. Answers have been given, but a deeper understanding of the range of phenomena to which the JE applies is necessary, both conceptually and in order to interpret the experiments in which it is used.

Parameter estimation for cardiovascular flow modeling of fetal circulation

The present paper represents a first methodological work for the construction of a robust and accurate algorithm for the solution of an inverse problem given by the identification of the parameters of a lumped mathematical model of fetal circulation introduced by G. Pennati et al. (1997). The underlying estimation techniques here applied are two global search meth- ods, respectively a Parameter Space Investigation (PSI) and the Ensemble Kalman Filter (EnKF), with a refinement performed with a local search method, i.e. Levenberg- Marquardt method (LM).

A Model for Urban Social Networks

Defining accurate and flexible models for real-world networks of human beings is instrumental to understand the observed properties of phenomena taking place across those networks and to support computer simulations of dynamic processes of interest for several areas of research - including computational epidemiology, which is recently high on the agenda. In this paper we present a flexible model to generate age-stratified and geo-referenced synthetic social networks on the basis of widely available aggregated demographic data and, possibly, of estimated age-based social mixing patterns.