The problem of reconstructing a piecewise constant function from a finite number of its Fourier coefficients perturbed by noise is considered. A reconstruction method, based on the computation of the Padè approximants to the Z-transform of the sequence of the noisy Fourier coefficients is proposed. The method is based on the remark that the distribution of the poles of the Padè approximants shows, asymptotically, clusters in the complex plane which allow the identification of the discontinuities of the function.

Endothelial cell (EC) migration is crucial for a wide range of processes including vascular wound healing, tumor angiogenesis, and the development of viable endovascular implants.

Graph structures nowadays pervasive Big Data. It is often useful to regroup suchclusters data incan clusters, according distinctive node features, and use are a representative elementinfor each cluster. In many real-world cases, be identified by to a set of connected features, and share use a representative element for eachfunction, cluster.

Started as a hyped technology a few years ago, IoT is now a reality providing sensing and computing capabilities from SCADA systems to households. At their core, IoT devices connect to the outside world to share sensed or computed data. However, the sensitivity and privacy of shared data has made access management a stringent need also for the IoT. In particular, continuous authentication could solve a few security issues, like session hijacking, via checking device legitimacy for each exchanged message and preventing attackers from pretending their actions came from authenticated devices.

Targeted drug delivery systems represent a promising strategy to treat localised disease with minimum impact on the surrounding tissue. In particular, polymeric nanocontainers have attracted major interest because of their structural and morphological advantages and the variety of polymers that can be used, allowing the synthesis of materials capable of responding to the biochemical alterations of the environment.

In this paper, the modal analysis model, made up by a linear combination of complex exponential functions, is considered. Padè approximants to the Z-transform of a noisy sample are then considered, and the asymptotic locus of their poles is studied. It turns out that this locus is strongly related to the complex exponentials of the model. By exploiting these properties, powerful methods for estimating the model parameters can be devised, which have both denoising and super-resolution capabilities.

Drug-coated balloons (DCBs) are used commonly for delivering drug into diseased arteries. When applied on the inner surface of an artery, drug is transported from the balloon into the multilayer arterial wall through diffusion and advection, where it is ultimately absorbed through binding reactions. Mathematical modeling of these mass transport processes has the potential to help understand and optimize balloon-based drug delivery, thereby ensuring both safety and efficacy.

Controlled release of a drug contained in a spherical polymer capsule is of significant interest in many fields of medicine. There is growing interest in tailoring the erosion properties of the drug to help control and optimize the drug release process. Theoretical understanding of the nature of drug release from a bioerodible capsule is, therefore, important for designing effective drug delivery systems.