Bistable defect structures in blue phase devices

Blue phases are liquid crystals made up by networks of defects, or disclination lines. While existing phase diagrams show a striking variety of competing metastable topologies for these networks, very little is known as to how to kinetically reach a target structure, or how to switch from one to the other, which is of paramount importance for devices. We theoretically identify two confined blue phase I systems in which by applying an appropriate series of electric field it is possible to select one of two bistable defect patterns.

The Knapsack Problem with forfeit sets

This work introduces a novel extension of the 0/1 Knapsack Problem in which we consider the existence of so-called forfeit sets. A forfeit set is a subset of items of arbitrary cardinality, such that including a number of its elements that exceeds a predefined allowance threshold implies some penalty costs to be paid in the objective function value. A global upper bound on these allowance violations is also considered.

De la Vallée Poussin interpolation method for image resizing

The aim of this talk is to show how de la Vallee Poussin type interpolation based on Chebyshev zeros of rst kind, can be applied to resize an arbitrary color digital image. In fact, using such kind of approximation, we get an image scaling method running for any desired scaling factor or size, in both downscaling and upscaling. The peculiarities and the performance of such method will be discussed.

Network, degeneracy and bow tie integrating paradigms and architectures to grasp the complexity of the immune system

Recently, the network paradigm, an application of graph theory to biology, has proven to be a powerful approach to gaining insights into biological complexity, and has catalyzed the advancement of systems biology. In this perspective and focusing on the immune system, we propose here a more comprehensive view to go beyond the concept of network.

Normalized compression distance to measure cortico-muscular synchronization

The neuronal functional connectivity is a complex and non-stationary phenomenon creating dynamic networks synchronization determining the brain states and needed to produce tasks. Here, as a measure that quantifies the synchronization between the neuronal electrical activity of two brain regions, we used the normalized compression distance (NCD), which is the length of the compressed file constituted by the concatenated two signals, normalized by the length of the two compressed files including each single signal.

Self-Attractive Semiflexible Polymers under an External Force Field

The dynamical response of a tethered semiflexible polymer with self-attractive interactions and subjected to an external force field is numerically investigated by varying stiffness and self-interaction strength. The chain is confined in two spatial dimensions and placed in contact with a heat bath described by the Brownian multi-particle collision method. For strong self-attraction the equilibrium conformations range from compact structures to double-stranded chains, and to rods when increasing the stiffness.

Encoding the states of interacting proteins to facilitate biological pathways reconstruction

Background: In a systems biology perspective, protein-protein interactions (PPI) are encoded in machine-readable formats to avoid issues encountered in their retrieval for the reconstruction of comprehensive interaction maps and biological pathways. However, the information stored in electronic formats currently used doesn't allow a valid automatic reconstruction of biological pathways.Results: We propose a logical model of PPI that takes into account the "state" of proteins before and after the interaction.

Different types of cell death in organismal aging and longevity: State of the art and possible systems biology approach

Cell death is as important as cell proliferation for cell turn-over, and susceptibility to cell death is affected by a number of parameters that change with time. A time-dependent derangement of such a crucial process, or even the simple cell loss mediated by cell death impinges upon aging and longevity. In this review we will discuss how cell death phenomena are modulated during aging and what is their possible role in the aging process.