The hierarchical organization of natural protein interaction networks confers self-organization properties on pseudocells.

Background Cell organization is governed and maintained via specific interactions among its constituent macromolecules. Comparison of the experimentally determined protein interaction networks in different model organisms has revealed little conservation of the specific edges linking ortholog proteins. Nevertheless, some topological characteristics of the graphs representing the networks - namely non-random degree distribution and high clustering coefficient - are shared by networks of distantly related organisms.

Novel risk predictor for thrombus deposition in abdominal aortic aneurysms

The identification of the basic mechanisms responsible for cardiovascular diseases stands as one of the most challenging problems in modern medical research including various mechanisms which encompass a broad spectrum of space and time scales. Major implications for clinical practice and pre-emptive medicine rely on the onset and development of intraluminal thrombus in which effective clinical therapies require synthetic risk predictors/indicators capable of informing real-time decision-making protocols.

Three-Dimensional Lattice Pseudo-Potentials for Multiphase Flow Simulations at High Density Ratios

It is shown that the combination of generalized Van der Waals equations of state with high-order discrete velocity lattices, permits to simulate the dynamics of liquid droplets at air-water density ratios, with very moderate levels of spurious currents near the droplet interface. Satisfactory agreement with experimental data on droplet collisions at density ratios of order thousand is reported.

Paradoxical ratcheting in cornstarch

In this paper, we demonstrate that vertically vibrating a plate in a cornstarch suspension causes the suspension to vigorously ratchet up the plate. We show that this is a necessary consequence of the fact that cornstarch in water is shear thickening: when the plate moves up it opposes gravity and so the fluid stiffens; when it moves down it works with gravity and so the fluid flows. This produces asymmetric ratcheting that opposes gravity.

AntiCheetah: Trustworthy computing in an outsourced (cheating) environment

The increasing need for performing expensive computations has motivated outsourced computing, as in crowdsourced applications leveraging worker cloud nodes. However, these outsourced computing nodes can potentially misbehave or fail. Exploiting the redundancy of nodes can help guaranteeing correctness and availability of results. This entails that reliable distributed computing can be achieved at the expense of convenience.

The Role of Very Low-Reynolds Hydrodynamics on the Transfer of Information Among Active Agents

We investigate the role of hydrodynamic interactions on the decision-making and leader-identification processes within a group of fifty small-size active individuals, immersed in a viscous fluid at very low Reynolds number, . A fraction of the individuals is informed about the spatial location of the target, and moves accordingly along a privileged trajectory. The rest of the group has no access to this information, but may draw indirect benefit by following the trajectory of the informed individuals, through a process of leader-identification.

Colloquium: Large scale simulations on GPU clusters

Graphics processing units (GPU) are currently used as a cost-effective platform forcomputer simulations and big-data processing. Large scale applications require thatmultiple GPUs work together but the efficiency obtained with cluster of GPUs is, at times,sub-optimal because the GPU features are not exploited at their best. We describe how itis possible to achieve an excellent efficiency for applications in statistical mechanics,particle dynamics and networks analysis by using suitable memory access patterns andmechanisms like CUDA streams, profiling tools, etc.