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We consider a mathematical model describing population dynamics of normal and abnormal cell densities with contact inhibition of cell growth from a theoretical point of view. In the first part of this paper, we discuss the global existence of a solution satisfying the segregation property in one space dimension for general initial data. Here, the term segregation property means that the different types of cells keep spatially segregated when the initial densities are segregated.

Extended versions of the Bourgain-Brezis-Mironescu theorems on the limit as s->1^- of the Gagliardo-Slobodeckij fractional seminorm are established in the Orlicz space setting. Our results hold for fractional Orlicz-Sobolev spaces built upon general Young functions, and complement those of [13], where Young functions satisfying the $\Delta_2$ and the $\nabla_2$ conditions are dealt with. The case of Young functions with an asymptotic linear growth is also considered in connection with the space of functions of bounded variation.

Pervasive mobile and low-end wireless technologies, such as radio-frequency identification (RFID), wireless sensor networks and the impending vehicular ad-hoc networks (VANETs), make the wireless scenario exciting and in full transformation. For all the above (and similar) technologies to fully unleash their potential in the industry and society, there are two pillars that cannot be overlooked: security and privacy. Both properties are especially relevant if we focus on ad-hoc wireless networks, where devices are required to cooperate - e.g.

In the framework of the exact factorization of the time-dependent electron-nuclear wave function, we investigate the possibility of solving the nuclear time-dependent Schrödinger equation based on trajectories. The nuclear equation is separated in a Hamilton-Jacobi equation for the phase of the wave function, and a continuity equation for its (squared) modulus. For illustrative adiabatic and nonadiabatic one-dimensional models, we implement a procedure to follow the evolution of the nuclear density along the characteristics of the Hamilton-Jacobi equation.

Tumor resistance to chemotherapy represents an important challenge in modern oncology. Although platinum (Pt)-based drugs have demonstrated excellent therapeutic potential, their effectiveness in a wide range of tumors is limited by the development of resistance mechanisms. One of these mechanisms includes increased cisplatin sequestration/efflux by the copper-transporting ATPase, ATP7B. However, targeting ATP7B to reduce Pt tolerance in tumors could represent a serious risk because suppression of ATP7B might compromise copper homeostasis, as happens in Wilson disease.

Using the new methodology introduced in a recent paper [D. Bini, T. Damour, and A. Geralico, Phys. Rev. Lett. 123, 231104 (2019)], we present the details of the computation of the conservative dynamics of gravitationally interacting binary systems at the fifth post-Newtonian (5PN) level, together with its extension at the fifth-and-a-half post-Newtonian level. We present also the sixth post-Newtonian (6PN) contribution to the third-post-Minkowskian (3PM) dynamics.

The optimal Orlicz target space is exhibited for embeddings of fractional-order Orlicz-Sobolev spaces in $R^n$. An improved embedding with an Orlicz-Lorentz target space, which is optimal in the broader class of all rearrangement-invariant spaces, is also established. Both spaces of order s in (0, 1), and higher-order spaces are considered. Related Hardy type inequalities are proposed as well.