In this work, we propose and explore a novel network-constraint survival methodology considering the Weibull accelerated failure time (AFT) model combined with a penalized likelihood approach for variable selection and estimation [2]. Our estimator explicitly incorporates the correlation patterns among predictors using a double penalty that promotes both sparsity and the grouping effect. In or- der to solve the structured sparse regression problems we present an efficient iterative computational algorithm based on proximal gradient descent method [1].

The Dirichlet-Ferguson measure is a cornerstone in nonparametric Bayesian statistics and the study of distributional properties of expectations with respect to such measure is an important line of research. In this paper we provide explicit upper bounds for the d2, the d3 and the convex distance between vectors whose components are means of the Dirichlet-Ferguson measure and a Gaussian random vector.

This contribution outlines current research aimed at developing models for personalized type 2 diabetes mellitus (T2D) prevention in the framework of the European project PRAESIIDIUM (Physics Informed Machine Learn-ing-Based Prediction and Reversion of Impaired Fasting Glucose Management) aimed at building a digital twin for preventing T2D in patients at risk.

In a subsoil bioremediation intervention air or oxygen is injected in the polluted region and then a model for unsaturated porous media it is required, based on the theory of the dynamics of multiphase fluids in porous media. In order to optmize the costs of the intervention it is useful to consider the gas as compressible and this fact introduces nonlinearity in the mathematical model. The physical problem is described by a system of equations and the unknowns are: pollutant; bacteria concentration; oxygen saturation and oxygen pressure.

Dissolution of drug from its solid form to a dissolved form is an important consideration in the design and optimization of drug delivery devices, particularly owing to the abundance of emerging compounds that are extremely poorly soluble. When the solid dosage form is encapsulated, for example by the porous walls of an implant, the impact of the encapsulant drug transport properties is a further confounding issue. In such a case, dissolution and diffusion work in tandem to control the release of drug.

This paper concerns the study of a non-smooth logistic regression function. The focus is on a high-dimensional binary response case by penalizing the decomposition of the unknown logit regression function on a wavelet basis of functions evaluated on the sampling design. Sample sizes are arbitrary (not necessarily dyadic) and we consider general designs. We study separable wavelet estimators, exploiting sparsity of wavelet decompositions for signals belonging to homogeneous Besov spaces, and using efficient iterative proximal gradient descent algorithms.

Exploiting the Infrared Atmospheric Sounder Interferometer (IASI) profiling capability for surface parameters, atmospheric temperature, and water vapour we have designed a new Water Deficit Index (wdi) to monitor drought and heatwaves. Because of climate change at a global level, drought is becoming a strong emergency also in countries which never experienced it, such as the Mediterranean mid-latitude area and, in particular, Italy. The last two years strongly affected the northern part of Italy, i.e. the Po Valley, causing high vegetation and soil water stress.

Real-world facility planning problems often require to tackle simultaneously network connectivity and zonal requirements, in order to guarantee an equitable provision of services and an efficient flow of goods, people and information among the facilities. Nonetheless, such challenges have not been addressed jointly so far. In this paper we explore the introduction of advanced network connectivity features and spatial-related requirements within Covering Location Problems.