H2020 Project ECOPOTENTIAL: making best use of remote sensing and in-situ observations to improve future ecosystem benefits

This poster has been presented at the first ILTER Open Science Meeting in Skukuza, Kruger National Park, South Africa, 9-13 October 2016 (https://na.eventscloud.com/ehome/156435), and describes the general purposes and organization of the H2020 project ECOPOTENTIAL (http://www.ecopotential-project.eu/)

Higher-order tail contributions to the energy and angular momentum fluxes in a two-body scattering process

The need for more and more accurate gravitational-wave templates requires taking into account all possible contributions to the emission of gravitational radiation from a binary system. Therefore, working within a multipolar-post-Minkowskian framework to describe the gravitational-wave field in terms of the source multipole moments, the dominant instantaneous effects should be supplemented by hereditary contributions arising from nonlinear interactions between the multipoles.

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm.

The poles of the heart and branchiomeric muscles of the face and neck are formed from the cardiopharyngeal mesoderm within the pharyngeal apparatus. They are disrupted in patients with 22q11.2 deletion syndrome, due to haploinsufficiency of TBX1, encoding a T-box transcription factor. Here, using single cell RNA-sequencing, we now identify a multilineage primed population within the cardiopharyngeal mesoderm, marked by Tbx1, which has bipotent properties to form cardiac and branchiomeric muscle cells.

Immunoinformatics based designing a multi-epitope vaccine against pathogenic Chandipura vesiculovirus

Chandipura vesiculovirus (CHPV) is a rapidly emerging pathogen responsible for causing acute encephalitis. Due to its widespread occurrence in Asian and African countries, this has become a global threat, and there is an urgent need to design an effective and nonallergenic vaccine against this pathogen. The present study aimed to develop a multi-epitope vaccine using an immunoinformatics approach. The conventional method of vaccine design involves large proteins or whole organism which leads to unnecessary antigenic load with increased chances of allergenic reactions.

From Infection to Immunity: Understanding the Response to SARS-CoV2 Through In-Silico Modeling

Background: Immune system conditions of the patient is a key factor in COVID-19 infection survival. A growing number of studies have focused on immunological determinants to develop better biomarkers for therapies. Aim: Studies of the insurgence of immunity is at the core of both SARS-CoV-2 vaccine development and therapies. This paper attempts to describe the insurgence (and the span) of immunity in COVID-19 at the population level by developing an in-silico model.

A time-modulated Hawkes process to model the spread of COVID-19 and the impact of countermeasures

Motivated by the recent outbreak of coronavirus (COVID-19), we propose a stochastic model of epidemic temporal growth and mitigation based on a time-modulated Hawkes process. The model is sufficiently rich to incorporate specific characteristics of the novel coronavirus, to capture the impact of undetected, asymptomatic and super-diffusive individuals, and especially to take into account time-varying counter-measures and detection efforts. Yet, it is simple enough to allow scalable and efficient computation of the temporal evolution of the epidemic, and exploration of what-if scenarios.

Frequency domain analysis of the gravitational wave energy loss in hyperbolic encounters

The energy radiated (without the 1.5PN tail contribution which requires a different treatment) by a binary system of compact objects moving in a hyperboliclike orbit is computed in the frequency domain through the second post-Newtonian level as an expansion in the large-eccentricity parameter up to next-to-next-to-leading order, completing the time domain corresponding information (fully known in closed form at the second post-Newtonian of accuracy).

COVID-19 cumulative incidence, intensive care, and mortality in Italian regions compared to selected European countries

Background: The high contagiousness and rapid spreading of the coronavirus disease 2019 (COVID-19) has caused a high number of critical to severe life-threatening cases, which required urgent hospital admission and treatment in intensive care units (ICUs). The pandemic has been a tough test for all European national health systems and their capability to provide an adequate reaction. Methods: The present work aims to reveal correlations between parameters such as COVID-19 incidence, ICU bed occupancy, ICU excess area, and mortality in Italian regions.

Theoretical model for diffusion-reaction based drug delivery from a multilayer spherical capsule

Controlled drug delivery from a multilayer spherical capsule is used for several therapeutic applications. Developing a theoretical understanding of mass transfer in the multilayer capsule is critical for understanding and optimizing targeted drug delivery. This paper presents an analytical solution for the mass transport problem in a general multilayer sphere involving diffusion as well as drug immobilization in various layers due to binding reactions.