In this paper, we consider the problem of estimating multiple Gaussian Graphical Models from high-dimensional datasets. We assume that these datasets are sampled from different distributions with the same conditional independence structure, but not the same precision matrix. We propose jewel, a joint data estimation method that uses a node-wise penalized regression approach. In particular, jewel uses a group Lasso penalty to simultaneously guarantee the resulting adjacency matrix's symmetry and the graphs' joint learning.

Extended versions of the Bourgain-Brezis-Mironescu theorems on the limit as s->1^- of the Gagliardo-Slobodeckij fractional seminorm are established in the Orlicz space setting. The results hold for fractional Orlicz-Sobolev spaces built upon general Young functions, as well. The case of Young functions with an asymptotic linear growth is also considered in connection with the space of functions of bounded variation. An extended version of the Maz'ya-Shaposhnikova theorem on the limit as s->0^+ of the Gagliardo-Slobodeckij fractional seminorm is established in the Orlicz space setting.

Mass spectrometry is a widely applied technology with a strong impact in the proteomics field. MALDI-TOF is a combined technology in mass spectrometry with many applications in characterizing biological samples from different sources, such as the identification of cancer biomarkers, the detection of food frauds, the identification of doping substances in athletes' fluids, and so on. The massive quantity of data, in the form of mass spectra, are often biased and altered by different sources of noise.

The existence of eigenfunctions for a class of fully anisotropic elliptic equations is established. The relevant equations are associated with constrained minimization problems for integral func- tionals depending on the gradient of competing functions through general anisotropic Young functions. In particular, the latter need neither be radial, nor have a polynomial growth, and are not even assumed to satisfy the so called \Delta_2-condition. In particular, our analysis requires the development of some new aspects of the theory of anisotropic Orlicz-Sobolev spaces.

The optimal Orlicz target space and the optimal rearrangement-invariant tar- get space are exhibited for embeddings of fractional-order Orlicz-Sobolev spaces W^{s,A}(R^n). Related Hardy type inequalities are proposed as well. Versions for frac- tional Orlicz-Sobolev seminorms of the Bourgain-Brezis-Mironescu theorem on the limit as s->1^- and of the Maz'ya-Shaposhnikova theorem on the limit as s ->0^+ are established. This is a joint work with Andrea Cianchi, Lubos Pick and Lenka Slavikova.

ZFP57 is required to maintain the germline-marked differential methylation at imprinting control regions (ICRs) in mouse embryonic stem cells (ESCs). Although DNA methylation has a key role in genomic imprinting, several imprinted genes are controlled by different mechanisms, and a comprehensive study of the relationship between DMR methylation and imprinted gene expression is lacking. To address the latter issue, we differentiated wild-type and Zfp57-/- hybrid mouse ESCs into neural precursor cells (NPCs) and evaluated allelic expression of imprinted genes.

The existence of eigenfunctions for a class of fully anisotropic elliptic equations is estab- lished. The relevant equations are associated with constrained minimization problems for inte- gral functionals depending on the gradient of competing functions through general anisotropic Young functions. In particular, the latter need neither be radial, nor have a polynomial growth, and are not even assumed to satisfy the so called 2-condition. In particular, our analysis re- quires the development of some new aspects of the theory of anisotropic Orlicz-Sobolev spaces. This is a joint work with G.

The non-equilibrium structural and dynamical properties of semiflexible polymers confined to two dimensions under oscillatory shear flow are investigated by Brownian multi-particle collision dynamics. Two different scenarios will be considered: Filaments with both fixed ends [1] and wall-anchored chains [2]. The results of the numerical studies will be presented and discussed. References [1] A. Lamura, R. G. Winkler Polymers 2019, 11, 737. DOI:10.3390/polym11040737 [2] A. Lamura, R. G. Winkler, G. Gompper pre-print 2021

We discuss the well-posedness of the "transient eddy current" magneto-quasi-static approximation of Maxwell's initial value problem with bounded and measurable conductivity, with sources, on a domain. We prove the existence and uniqueness of weak solutions, and we provide global Hölder estimates for the magnetic part.

Over the last decade, significant attention has been devoted to Closed-Loop Supply Chain (CLSC) design problems. As such, this review aims at assessing whether the current modelling approaches for CLSC problems can support the transition towards a Circular Economy at a supply chain level. The paper comprehensively assesses the extent to which existing modelling approaches evaluate the performance of supply chains across the complete spectrum of sustainability dimensions.