On a One-Dimensional Hydrodynamic Model for Semiconductors with Field-Dependent Mobility

We consider a one-dimensional, isentropic, hydrodynamical model for a unipolar semiconductor, with the mobility depending on the electric field. The mobility is related to the momentum relaxation time, and field-dependent mobility models are commonly used to describe the occurrence of saturation velocity, that is, a limit value for the electron mean velocity as the electric field increases. For the steady state system, we prove the existence of smooth solutions in the subsonic case, with a suitable assumption on the mobility function.

Analisys of a nonlinear model arising in chemical aggression of marble

We present a simple model describing the chemical aggression undergone by calcium carbonate rocks in presence of acid atmosphere. A large literature is available on the deterioration processes of building stones, in particular in connection with problems concerning historical buildings in the field of Cultural Heritage. It is well known that the greatest aggression is caused by sulfur dioxide and nitrate. In this paper we consider the corrosion caused by sulphur dioxide, which, reacting with calcium carbonate, produces gypsum.

Semiflexible polymers under oscillatory shear flow

The non-equilibrium structural and dynamical properties of semiflexible polymers confined to two dimensions under oscillatory shear flow are investigated by Brownian multi-particle collision dynamics. Two different scenarios will be considered: Filaments with both fixed ends [1] and wall-anchored chains [2]. The results of the numerical studies will be presented and discussed. References [1] A. Lamura, R. G. Winkler Polymers 2019, 11, 737. DOI:10.3390/polym11040737 [2] A. Lamura, R. G. Winkler, G. Gompper pre-print 2021

Wall-anchored semiflexible polymer under large amplitude oscillatory shear flow

The properties of semiflexible polymers tethered by one end to an impenetrable wall and exposed to oscillatory shear flow are investigated by mesoscale simulations. A polymer, confined in two dimensions, is described by a linear bead-spring chain, and fluid interactions are incorporated by the Brownian multiparticle collision dynamics approach. At small strain, the polymers follow the applied flow field. However, at high strain, we find a strongly nonlinear response with major conformational changes.

Game of neutrophils: modeling the balance between apoptosis and necrosis

Background: Neutrophils are one of the key players in the human innate immune system (HIIS). In the event of an insult where the body is exposed to inflammation triggering moieties (ITMs), neutrophils are mobilized towards the site of insult and antagonize the inflammation. If the inflammation is cleared, neutrophils go into a programmed death called apoptosis.

Potential predictors of type-2 diabetes risk: machine learning, synthetic data and wearable health devices

Background: The aim of a recent research project was the investigation of the mechanisms involved in the onset of type 2 diabetes in the absence of familiarity. This has led to the development of a computational model that recapitulates the aetiology of the disease and simulates the immunological and metabolic alterations linked to type-2 diabetes subjected to clinical, physiological, and behavioural features of prototypical human individuals. Results: We analysed the time course of 46,170 virtual subjects, experiencing different lifestyle conditions.

High-resolution analysis of the human retina miRNome reveals isomiR variations and novel microRNAs

MicroRNAs play a fundamental role in retinal development and function. To characterise the miRNome of the human retina, we carried out deep sequencing analysis on sixteen individuals. We established the catalogue of retina-expressed miRNAs, determined their relative abundance and found that a small number of miRNAs accounts for almost 90% of the retina miRNome. We discovered more than 3000 miRNA variants (isomiRs), encompassing a wide range of sequence variations, which include seed modifications that are predicted to have an impact on miRNA action.

GeenaR: A Web Tool for Reproducible MALDI-TOF Analysis

Mass spectrometry is a widely applied technology with a strong impact in the proteomics field. MALDI-TOF is a combined technology in mass spectrometry with many applications in characterizing biological samples from different sources, such as the identification of cancer biomarkers, the detection of food frauds, the identification of doping substances in athletes' fluids, and so on. The massive quantity of data, in the form of mass spectra, are often biased and altered by different sources of noise.