The rheology of pressure-driven flows of two-dimensional dense monodisperse emulsions in neutral wetting microchannels is investigated by means of mesoscopic lattice Boltzmann simulations, capable of handling large collections of droplets, in the order of several hundreds. The simulations reveal that the fluidization of the emulsion proceeds through a sequence of discrete steps, characterized by yielding events whereby layers of droplets start rolling over each other, thus leading to sudden drops of the relative effective viscosity.

Background A subset of individuals affected by imprinting disorders displays multi-locus imprinting disturbances (MLID). MLID has been associated with maternal-effect variants that alter the maintenance of methylation at germline-derived differentially methylated regions (gDMRs) in early embryogenesis. Pedigrees of individuals with MLID also include siblings with healthy phenotype.

The Wigner rotations arising from the combination of boosts along two different directions arc rederived from a relative boost point of view and applied to study gyroscope spin precession along timelike geodesics in a Kerr spacetime. First this helps to clarify the geometrical properties of Marck's recipe for reducing the equations of parallel transport along such world lines expressed in terms of the constants of the motion to a single differential equation for the essential planar rotation.

We investigate the motion of uncharged particles scattered by a binary system consisting of extremely charged black holes in equilibrium as described by the Majumdar-Papapetrou solution. We focus on unbound orbits confined to the plane containing both black holes. We consider the two complementary situations of particles approaching the system along a direction parallel to the axis where the black holes are displaced and orthogonal to it.

We propose an approach to the numerical simulation of thin-film flows based on the lattice Boltzmann method. We outline the basic features of the method, show in which limits the expected thin-film equations are recovered, and perform validation tests. The numerical scheme is applied to the viscous Rayleigh-Taylor instability of a thin film and to the spreading of a sessile drop toward its equilibrium contact angle configuration. We show that the Cox-Voinov law is satisfied and that the effect of a tunable slip length on the substrate is correctly captured.

Single-cell RNA-seq (scRNAseq) is a powerful tool to study heterogeneity of cells. Recently, several clustering based methods have been proposed to identify distinct cell populations. These methods are based on different statistical models and usually require to perform several additional steps, such as preprocessing or dimension reduction, before applying the clustering algorithm. Individual steps are often controlled by method-specific parameters, permitting the method to be used in different modes on the same datasets, depending on the user choices.

We analytically compute the gravitational self-force correction to the gyroscope precession along slightly eccentric equatorial orbits in the Kerr spacetime, generalizing previous results for the Schwarzs-child spacetime. Our results are accurate through the 9.5 post-Newtonian order and to second order in both eccentricity and rotation parameter. We also provide a post-Newtonian check of our results based on the currently known Hamiltonian for spinning binaries.

In this study, we developed a predictive model of in vivo stent based drug release and distribution that is capable of providing useful insights into performance. In a combined mathematical modelling and experimental approach, we created two novel sirolimus-eluting stent coatings with quite distinct doses and release kinetics. Using readily measurable in vitro data, we then generated parameterised mathematical models of drug release. These were then used to simulate in vivo drug uptake and retention.

Social Web Services (SWSs) constitute a novel paradigm of service-oriented computing, where Web services, just like humans, sign up in social networks that guarantee, e.g., better service discovery for users and faster replacement in case of service failures. In past work, composition of SWSs was mainly supported by specialised social networks of competitor services and cooperating ones. In this work, we continue this line of research, by proposing a novel SWSs composition procedure driven by the SWSs reputation.