Less Is Enough: Assessment of the Random Sampling Method for the Analysis of Magnetoencephalography (MEG) Data

Magnetoencephalography (MEG) aims at reconstructing the unknown neuroelectric activity in the brain from non-invasive measurements of the magnetic field induced by neural sources. The solution of this ill-posed, ill-conditioned inverse problem is usually dealt with using regularization techniques that are often time-consuming, and computationally and memory storage demanding. In this paper we analyze how a slimmer procedure, random sampling, affects the estimation of the brain activity generated by both synthetic and real sources.

A fast and Robust spectrogram reassignment method

The improvement of the readability of time-frequency transforms is an important topic in the field of fast-oscillating signal processing. The reassignment method is often used due to its adaptivity to different transforms and nice formal properties. However, it strongly depends on the selection of the analysis window and it requires the computation of the same transform using three different but well-defined windows.

Effects of Advective-Diffusive Transport of Multiple Chemoattractants on Motility of Engineered Chemosensory Particles in Fluidic Environments

Motility behavior of an engineered chemosensory particle (ECP) in fluidic environments is driven by its responses to chemical stimuli. One of the challenges to understanding such behaviors lies in tracking changes in chemical signal gradients of chemoattractants and ECP-fluid dynamics as the fluid is continuously disturbed by ECP motion. To address this challenge, we introduce a new multiscale numerical model to simulate chemotactic swimming of an ECP in confined fluidic environments by accounting for motility-induced disturbances in spatiotemporal chemoattractant distributions.

Design, Implementation and Test of a Flexible Tor-oriented Web Mining Toolkit

Searching and retrieving information from the Web is a primary activity needed to monitor the development and usage of Web resources. Possible benefits include improving user experience (e.g. by optimizing query results) and enforcing data/user security (e.g. by identifying harmful websites). Motivated by the lack of ready-to-use solutions, in this paper we present a flexible and accessible toolkit for structure and content mining, able to crawl, download, extract and index resources from the Web.

Fixation probabilities in weakly compressible fluid flows

Competition between biological species in marine environments is affected by the motion of the surrounding fluid. An effective 2D compressibility can arise, for example, from the convergence and divergence of water masses at the depth at which passively traveling photosynthetic organisms are restricted to live. In this report, we seek to quantitatively study genetics under flow. To this end, we couple an off-lattice agent-based simulation of two populations in 1D to a weakly compressible velocity field--first a sine wave and then a shell model of turbulence.

Combined effects of fluid type and particle shape on particles flow in microfluidic platforms

Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently accommodating the non-Newtonian nature of the body fluid and the non-uniform geometric shapes of the CTCs.

Statistical properties of thermally expandable particles in soft-turbulence Rayleigh-Bénard convection

The dynamics of inertial particles in Rayleigh-Benard convection, where both particles and fluid exhibit thermal expansion, is studied using direct numerical simulations (DNS) in the soft-turbulence regime. We consider the effect of particles with a thermal expansion coefficient larger than that of the fluid, causing particles to become lighter than the fluid near the hot bottom plate and heavier than the fluid near the cold top plate.

HDAC2-dependent miRNA signature in acute myeloid leukemia

Acute myeloid leukemia (AML) arises from a complex sequence of biological and finely orchestrated events that are still poorly understood. Increasingly, epigenetic studies are providing exciting findings that may be exploited in promising and personalized cutting-edge therapies. A more appropriate and broader screening of possible players in cancer could identify a master molecular mechanism in AML. Here, we build on our previously published study by evaluating a histone deacetylase (HDAC)2-mediated miRNA regulatory network in U937 leukemic cells.

New gravitational self-force analytical results for eccentric equatorial orbits around a Kerr black hole: Gyroscope precession

We analytically compute the gravitational self-force correction to the gyroscope precession along slightly eccentric equatorial orbits in the Kerr spacetime, generalizing previous results for the Schwarzs-child spacetime. Our results are accurate through the 9.5 post-Newtonian order and to second order in both eccentricity and rotation parameter. We also provide a post-Newtonian check of our results based on the currently known Hamiltonian for spinning binaries.