D3-4 Health

Progetto: D3-4-Health

«Digital Driven Diagnostics, prognostics and therapeutics for sustainable Health care»

DD MUR n.931 del 06/06/2022

• Finanziamento di «Iniziative» di ricerca con l’obiettivo di mettere a sistema, in chiave innovativa, il potenziamento della ricerca sulle tecnologie abilitanti in ambito sanitario, al fine di migliorare la diagnosi, il monitoraggio e le cure, incluse quelle riabilitative.

Verbale 1/2023

1. Iniziative per il centenario del CNR
2. Giornata IAC del 2023
3. Logo di Istituto
4. Gestione/organizzazione degli spazi comuni nelle varie sedi
5. Situazione progetti
6. Varie ed eventuali.

PASQUA D'AMBRA alla conferenza PDP 2023

d'ambra

Si è svolta dal 1° al 3 marzo la 31ma Euromicro International Conference on Parallel, Distributed, and Network-Based Processing PDP 2023.

L'evento era svolto nell'ambito delle attività di disseminazione del progetto ADMIRE finanziato da Horizon 2020 JTI-EuroHPC.

Tra i keynote speech anche quello della dirigente di ricerca dell'IAC Pasqua D'Ambra. L'intervento è riascoltabile al link in calce.

 

 

Spontaneous motility of passive emulsion droplets in polar active gels

We study by computer simulations the dynamics of a droplet of passive, isotropic fluid, embedded in a polar active gel. The latter represents a fluid of active force dipoles, which exert either contractile or extensile stresses on their surroundings, modelling for instance a suspension of cytoskeletal filaments and molecular motors. When the polarisation of the active gel is anchored normal to the droplet at its surface, the nematic elasticity of the active gel drives the formation of a hedgehog defect; this defect then drives an active flow which propels the droplet forward.

A minimal physical model captures the shapes of crawling cells

Cell motility in higher organisms (eukaryotes) is crucial to biological functions ranging from wound healing to immune response, and also implicated in diseases such as cancer. For cells crawling on hard surfaces, significant insights into motility have been gained from experiments replicating such motion in vitro. Such experiments show that crawling uses a combination of actin treadmilling (polymerization), which pushes the front of a cell forward, and myosin-induced stress (contractility), which retracts the rear.

Active Model H: Scalar Active Matter in a Momentum-Conserving Fluid

We present a continuum theory of self-propelled particles, without alignment interactions, in a momentum-conserving solvent. To address phase separation, we introduce a dimensionless scalar concentration field ? with advective-diffusive dynamics. Activity creates a contribution ? to the deviatoric stress, where is odd under time reversal and d is the number of spatial dimensions; this causes an effective interfacial tension contribution that is negative for contractile swimmers.

Build up of yield stress fluids via chaotic emulsification

Stabilised dense emulsions display a rich phenomenology connecting microstructure and rheology. In this work, we study how an emulsion with a finite yield stress can be built via large-scale stirring. By gradually increasing the volume fraction of the dispersed minority phase, under the constant action of a stirring force, we are able to achieve a volume fraction close to 80%. Despite the fact that our system is highly concentrated and not yet turbulent we observe a droplet size distribution consistent with the -10/3 scaling, often associated with inertial range droplets breakup.

Drag and lift coefficients of ellipsoidal particles under rarefied flow conditions

The capability to simulate a two-way coupled interaction between a rarefied gas and an arbitrary-shaped colloidal particle is important for many practical applications, such as aerospace engineering, lung drug delivery, and semiconductor manufacturing. By means of numerical simulations based on the direct-simulation Monte Carlo (DSMC) method, we investigate the influence of the orientation of the particle and rarefaction on the drag and lift coefficients, in the case of prolate and oblate ellipsoidal particles immersed in a uniform ambient flow.