This paper describes a collocation method for solving numerically a singular integral equation with Cauchy and Volterra operators, associated with a proper constraint condition. The numerical method is based on the transformation of the given integral problem into a hypersingular integral equation and then applying a collocation method to solve the latter equation. Convergence of the resulting method is then discussed, and optimal convergence rates for the collocation and discrete collocation methods are given in suitable weighted Sobolev spaces.

Human blood flow is a multiscale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models either involve a homogeneous fluid and cannot track particulate effects or describe a relatively small number of cells with high resolution but are incapable to reach relevant time and length scales. Our approach is to simplify much further than existing particulate models.