Towards a digital twin for personalized diabetes prevention: the PRAESIIDIUM project

This contribution outlines current research aimed at developing models for personalized type 2 diabetes mellitus (T2D) prevention in the framework of the European project PRAESIIDIUM (Physics Informed Machine Learn-ing-Based Prediction and Reversion of Impaired Fasting Glucose Management) aimed at building a digital twin for preventing T2D in patients at risk.

Numerical simulation of a compressible gas flow in porous media bioremendiation

In a subsoil bioremediation intervention air or oxygen is injected in the polluted region and then a model for unsaturated porous media it is required, based on the theory of the dynamics of multiphase fluids in porous media. In order to optmize the costs of the intervention it is useful to consider the gas as compressible and this fact introduces nonlinearity in the mathematical model. The physical problem is described by a system of equations and the unknowns are: pollutant; bacteria concentration; oxygen saturation and oxygen pressure.

A generalized mean-field game model for the dynamics of pedestrians with limited predictive abilities

This paper investigates the model for pedestrian flow firstly proposed in [Cristiani, Priuli, and Tosin, SIAM J. Appl. Math., 75:605-629, 2015]. The model assumes that each individual in the crowd moves in a known domain, aiming at minimizing a given cost functional. Both the pedestrian dynamics and the cost functional itself depend on the position of the whole crowd. In addition, pedestrians are assumed to have predictive abilities, but limited in time.

Using frames in statistical signal recovering

Overcomplete representations such as wavelets and windowed Fourier expansions have become mainstays of modern statistical data analysis. Here we derive expressions for the mean quadratic risk of shrinkage estimators in the context of general finite frames, which include any fullrank linear expansion of vector data in a finite-dimensional setting. We provide several new results and practical estimation procedures that take into account the geometric correlation structure of frame elements.

A new frame based de-noising procedure for fast oscillating signals

In recent years there has been a growing interest in frame based de-noising procedures. The advantage of frames with respect to classical orthonor- mal bases (e.g. wavelet, Fourier, polynomial) is that they can furnish an efficient representation of a more broad class of signals. For example, signals which have fast oscillating behavior as sonar, radar, EEG, stock market, audio and speech are much more well represented by a frame (with similar oscillating characteristic) than by a classical wavelet basis, although the frame representation for such kind of signals can be not properly sparse.

An all-densities pedestrian simulator based on a dynamic evaluation of the interpersonal distances

In this paper we deal with pedestrian modeling, aiming at simulating crowd behavior in normal and emergency scenarios, including highly congested mass events. We are specifically concerned with a new agent-based, continuous-in-space, discrete-in-time, nondifferential model, where pedestrians have finite size and are compressible to a certain extent. The model also takes into account the pushing behavior appearing at extremely high densities. The main novelty is that pedestrians are not assumed to generate any kind of "field" which governs the dynamics of the others in the space around them.

An overview of some mathematical techniques and problems linking 3D vision to 3D printing

Computer Vision and 3D printing have rapidly evolved in the last 10 years but interactions among them have been very limited so far, despite the fact that they share several mathematical techniques. We try to fill the gap presenting an overview of some techniques for Shape-from-Shading problems as well as for 3D printing with an emphasis on the approaches based on nonlinear partial differential equations and optimization. We also sketch possible couplings to complete the process of object manufacturing starting from one or more images of the object and ending with its final 3D print.

Quantitative Multidimensional Central Limit Theorems for Means of the Dirichlet-Ferguson Measure

The Dirichlet-Ferguson measure is a cornerstone in nonparametric Bayesian statistics and the study of distributional properties of expectations with respect to such measure is an important line of research. In this paper we provide explicit upper bounds for the d2, the d3 and the convex distance between vectors whose components are means of the Dirichlet-Ferguson measure and a Gaussian random vector.

Modelling sea ice and melt ponds evolution

We present a mathematical model describing the evolution of sea ice and meltwater during summer. The system is described by two coupled partial differential equations for the ice thickness h(x,t) and pond depth w(x,t) fields. The model is similar, in principle, to the one put forward by Luthije et al. (2006), but it features i) a modified melting term, ii) a non-uniform seepage rate of meltwater through the porous ice medium and a minimal coupling with the atmosphere via a surface wind shear term, ?s (Scagliarini et al. 2020).