Articolo in rivista

Heuristic approaches for the Minimum Labelling Hamiltonian Cycle Problem

Given a graph G with a label (color) assigned to each edge (not necessarily properly) we look for an hamiltonian cycle of G with the minimum number of different colors. The problem has several applications in telecommunication networks, electric networks, multimodal transportation networks, among…

CTLs' repertoire shaping in the thymus: A Monte Carlo simulation

Motivation: The human immune system evolved a multi-layered control mechanism to eliminate self-reactive cells. Of these so-called tolerance induction mechanisms, lymphocytes T education in the thymus gland represents the very first one. This complicated process is not fully understood and…

Reaction Spreading in Systems With Anomalous Diffusion

We briefly review some aspects of the anomalous diffusion, and its relevance in reactive systems. In particular we consider strong anomalous diffusion characterized by the moment behaviour <(x(t)(q)> similar to t(qv)(q), where v(q) is a non constant function, and we discuss its consequences.…

Splitting and composition methods for explicit time-dependence in separable dynamical systems

We consider splitting methods for the numerical integration of separable non-autonomous differential equations. In recent years, splitting methods have been extensively used as geometric numerical integrators showing excellent performances (both qualitatively and quantitatively) when applied on…

Modeling ATP-mediated endothelial cell elongation on line patterns

Endothelial cell (EC) migration is crucial for a wide range of processes including vascular wound healing, tumor angiogenesis, and the development of viable endovascular implants. We have previously demonstrated that ECs cultured on 15-?m wide adhesive line patterns exhibit three distinct migration…

DSMC-LBM mapping scheme for rarefied and non-rarefied gas flows

We present the formulation of a kinetic mapping scheme between the Direct Simulation Monte Carlo (DSMC) and the Lattice Boltzmann Method (LBM) which is at the basis of the hybrid model used to couple the two methods in view of efficiently and accurately simulate isothermal flows characterized by…

An iterative algorithm with joint sparsity constraints for magnetic tomography

Magnetic tomography is an ill-posed and ill-conditioned inverse problem since, in general, the solution is non-unique and the measured magnetic field is affected by high noise. We use a joint sparsity constraint to regularize the magnetic inverse problem. This leads to a minimization problem whose…

Quantifying the relevance of different mediators in the human immune cell network

Motivation: Immune cells coordinate their efforts for the correct and efficient functioning of the immune system (IS). Each cell type plays a distinct role and communicates with other cell types through mediators such as cytokines, chemokines and hormones, among others, that are crucial for the…

Relativistic Tidal Acceleration of Astrophysical Jets

Within the framework of general relativity, we investigate the tidal acceleration of astrophysical jets relative to the central collapsed configuration ("Kerr source"). To simplify matters, we neglect electromagnetic forces throughout; however, these must be included in a complete analysis. The…

Fusing in vivo and ex vivo NMR sources of information for brain tumor classification

In this study we classify short echo-time brain magnetic resonance spectroscopic imaging (MRSI) data by applying a model-based canonical correlation analyses algorithm and by using, as prior knowledge, multimodal sources of information coming from high-resolution magic angle spinning (HR-MAS), MRSI…