Articolo in rivista

Chromatin and transcriptional response to loss of TBX1 in differentiating mouse P19Cl6 and embryonic stem cells

The T-box transcription factor TBX1 has critical roles in the cardiopharyngeal lineage and the gene is haploinsufficient in DiGeorge syndrome, a typical developmental anomaly of the pharyngeal apparatus. Despite almost two decades of research, if and how TBX1 function triggers chromatin remodeling…

Model independent pre-processing of X-ray powder diffraction profiles

Precise knowledge of X-ray diffraction profile shape is crucial in the investigation of the properties of matter in crystals powder. Line-broadening analysis is the fourth pre-processing step in most of the full powder pattern fitting softwares. The final result of line-broadening analysis strongly…

Multiphase modeling and qualitative analysis of the growth of tumor cords

In this paper a macroscopic model of tumor cord growth is developed, relying on the mathematical theory of deformable porous media. Tumor is modeled as a saturated mixture of proliferating cells, extracellular fluid and extracellular matrix, that occupies a spatial region close to a blood vessel…

Godunov-type approximation for a general resonant balance law with large data

We consider the Cauchy problem for the 2 x 2 nonstrictly hyperbolic system [...] For possiblylarge, discontinuous and resonant data, the generalized solution to the Riemann problem is introduced, interaction estimates are carried out using an original change of variables and the convergence of…

InSAR Meteorology: High-Resolution Geodetic Data Can Increase Atmospheric Predictability

The present study assesses the added value of high-resolution maps of precipitable water vapor, computed from synthetic aperture radar interferograms , in short-range atmospheric predictability. A large set of images, in different weather conditions, produced by Sentinel-1A in a very well monitored…

Lattice mesoscopic model of dynamically heterogeneous fluids

We introduce a mesoscopic three-dimensional lattice Boltzmann model which attempts to mimic the physical features associated with cage effects in dynamically heterogeneous fluids. To this purpose, we extend the standard lattice Boltzmann dynamics with self-consistent constraints based on the…

Is this the right normalization? A diagnostic tool for ChIP-seq normalization

Background: Chip-seq experiments are becoming a standard approach for genome-wide profiling protein-DNA interactions, such as detecting transcription factor binding sites, histone modification marks and RNA Polymerase II occupancy. However, when comparing a ChIP sample versus a control sample, such…

Existence theory for nonclassical entropy solutions:

We provide a general approach to deal with entropy solutions to scalar conservation laws presenting nonclassical shocks.

Numerical High-Field Limits in Two-Stream Kinetic Models and 1D Aggregation Equations

Numerical resolution of two-stream kinetic models in a strong aggregative setting is considered. To illustrate our approach, we consider a one-dimensional kinetic model for chemotaxis in hydrodynamic scaling and the high field limit of the Vlasov-Poisson-Fokker-Planck system. A difficulty is that,…

A Sobolev inequality with reciprocal weights

We give a Sobolev inequality with the weight K(x) belonging to the class A_2\cap G_n for the function |u|^t and the weight K(x)^{-1} for |u|^2. The constant in the relevant inequality is seen to depend on the G_n and A_2 constants of the weight.