Presentazione

Mathematical models and methods in drug delivery systems

We propose a novel in-silico model for computing drug release from multi-layer capsules. The diffusion problem in such heterogeneous layer-by-layer composite medium is described by a system of coupled partial differential equations, which we solve analytically using separation of variables. In…

Retrieval of surface emissivity from FORUM-EE9 simulated measurements: optimization of constraints

We report the results of the regularization of the surface emissivity for the FORUM instrument.

Computational requirements of large-scale agent-based models

From un-realistic to quasi-realistic rules for trading in a microscopic model of financial markets with N>>1 assets

PDAE models of electric networks containing semiconductor devices

A numerical model of an experiment of iron corrosion

Discrete events simulation of a flexible service for people transportation

An easy-to-use numerical approach for simulating traffic flow on networks

A two-layer model for drug delivery from a transdermal patch

A two-phasemathematical model describing the dynamics of a substance between two coupled media of different properties and dimensions is presented. A system of partial differential equations describes the diffusion and the binding/unbinding processes in both layers. Additional flux continuity at…

Gene regulatory network modeling of macrophage polarization supports the continuum hypothesis of phenotype differentiation states

Macrophages derived from monocyte precursors undergo specific polarization processes being influenced by the local tissue environment: classically-activated (M1) macrophages, showing a pro-inflammatory activity affecting effector cells in Th1 cellular immune responses; and alternatively-activated (…