Abstract
Background: The main goal of the whole transcriptome analysis is to correctly identify all expressed transcripts within a specific cell/tissue- at a particular stage and condition - to determine their structures and to measure their abundances. RNA-seq data promise to allow identification and quantification of transcriptome at unprecedented level of resolution, accuracy and low cost. Several computational methods have been proposed to achieve such purposes. However, it is still not clear which promises are already met and which challenges are still open and require further methodological developments.
Anno
2014
Autori IAC
Tipo pubblicazione
Altri Autori
Angelini, Claudia; De Canditiis, Daniela; De Feis, Italia
Editore
BioMed Central,
Rivista
BMC bioinformatics