Articolo in rivista

High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction In Vitro and in Mouse Retina

Retinal gene therapy based on adeno-associated viral (AAV) vectors is safe and efficient in humans. The low intrinsic DNA transfer capacity of AAV has been expanded by dual vectors where a large expression cassette is split in two halves independently packaged in two AAV vectors. Dual AAV…

A result of existence and uniqueness for an integro-differential system in magneto-viscoelasticity

Discussion paper, a self-adapting and altitude-dependent regularization method for atmospheric profile retrievals

Tropospheric ozone retrieval from thermal infrared nadir satellite measurements: Towards more adaptability of the constraint using a self-adapting regularization.

We developed a Self-Adapting Constraint Retrieval Scheme (SACRS) to retrieve ozone profiles from nadir infrared satellite measurements. In this algorithm, the constraint is variable in altitude and adapted automatically for each individual measurement. The algorithm is tested on synthetic…

On the wake dynamics of a propeller operating in drift

The onset and the nature of dynamic instabilities experienced by the wake of a marine propeller set in oblique flow are investigated by means of detached eddy simulations. In particular, the destabilization process is inspected by a systematic comparison of the wake morphology of a propeller…

Modeling of mass dynamics in arterial drug-eluting stents

Acoustic-propagation properties of methane clathrate hydrates from non-equilibrium molecular dynamics

Given methane hydrates' importance in marine sediments, as well as the widespread use of seabed acoustic-signaling methods in oil and gas exploration, the elastic characterization of these materials is particularly relevant. A greater understanding of the properties governing phonon, sound, and…

A novel variant in the 3' untranslated region of the CDK4 gene: Interference with microRNA target sites and role in increased risk of cutaneous melanoma

Pedestrian flows in bounded domains with obstacles

Discrete fluidization of dense monodisperse emulsions in neutral wetting microchannels

The rheology of pressure-driven flows of two-dimensional dense monodisperse emulsions in neutral wetting microchannels is investigated by means of mesoscopic lattice Boltzmann simulations, capable of handling large collections of droplets, in the order of several hundreds. The simulations reveal…