Articolo in rivista

Lattice Boltzmann model for anisotropic liquid-solid phase transition

By improving a one-dimensional model proposed by De Fabritiis, Mancini, Mansutti and Succi in 1998, we develop a simple reaction model for liquid-solid phase transitions in the context of the lattice Boltzmann method with enhanced collisions.Calculations for a two-dimensional test problem of…

Modeling dual drug delivery from eluting stents: the influence of non-linear binding competition and non-uniform drug loading

Objective There is increasing interest in simultaneous endovascular delivery of more than one drug from a drug-loaded stent into a diseased artery. There may be an opportunity to obtain a therapeutically desirable uptake profile of the two drugs over time by appropriate design of the initial drug…

Alzheimer's disease: a mathematical model for onset and progression

In this article we propose a mathematical model for the onset and progression of Alzheimer's disease based on transport and diffusion equations. We regard brain neurons as a continuous medium and structure them by their degree of malfunctioning. Two different mechanisms are assumed to be relevant…

Wavelets and pde for image denoising

Intermittency in turbulence: Computing the scaling exponents in shell models

We discuss a stochastic closure for the equation of motion satisfied by multiscale correlation functions in the framework of shell models of turbulence. We present a plausible closure scheme to calculate the anomalous scaling exponents of structure functions by using the exact constraints imposed…

Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach

The SARS-CoV-2 non-structural protein 13 (nsp13) helicase is an essential enzyme for viral replication and has been identified as an attractive target for the development of new antiviral drugs. In detail, the helicase catalyzes the unwinding of double-stranded DNA or RNA in a 5? to 3? direction…

Exploring and analyzing the tor hidden services graph

The exploration and analysis of Web graphs has flourished in the recent past, producing a large number of relevant and interesting research results. However, the unique characteristics of the Tor network limit the applicability of standard techniques and demand for specific algorithms to explore…

Detection of Gaussian signals via hexagonal sensor networks

Simulating the ruin probability of risk processes with delay in claim settlement

Using importance sampling we give an asymptotic efficient simulation law for risk processes with delayed claims

Mechanotransduction map: simulation model, molecular pathway, gene set

Motivation: Mechanotransduction-the ability to output a biochemical signal from a mechanical input-is related to the initiation and progression of a broad spectrum of molecular events. Yet, the characterization of mechanotransduction lacks some of the most basic tools as, for instance, it can…