Articolo in rivista

The phenotypic variations of multi-locus imprinting disturbances associated with maternal-effect variants of NLRP5 range from overt imprinting disorder to apparently healthy phenotype

Background A subset of individuals affected by imprinting disorders displays multi-locus imprinting disturbances (MLID). MLID has been associated with maternal-effect variants that alter the maintenance of methylation at germline-derived differentially methylated regions (gDMRs) in early…

The influence of the wind forcing and of the changing of the Coriolis parameter on the Ross Sea tidal circulation

A tabu search approach for scheduling hazmat shipments

Vehicle routing and scheduling are two main issues in the hazardous material (hazmat) transportation problem. In this paper, we study the problem of managing a set of hazmat transportation requests in terms of hazmat shipment route selection and actual departure time definition. For each hazmat…

Some Remarks about the Hilbert Transform

In this paper we present som eremarks about the Hilbert transform on the real line and its numerical approximation, in connection with its application in signal processing.

Transient L1 error estimates for well-balanced schemes on non-resonant scalar balance laws

The ability of Well-Balanced (WB) schemes to capture very accurately steady-state regimes of non-resonant hyperbolic systems of balance laws has been thoroughly illustrated since its introduction by Greenberg and LeRoux (1996) [15] (see also the anterior WB Glimm scheme in E, 1992 [8]). This paper…

A Fast Algorithm for Computing the Smallest Eigenvalue of a Symmetric Positive Definite Toeplitz Matrix

Near-critical reflection of internal waves

Internal waves describe the (linear) response of an incompressible sta- bly stratified fluid to small perturbations. The inclination of their group velocity with respect to the vertical is completely determined by their frequency. Therefore the reflection on a sloping boundary cannot follow…

Relativistic lattice Boltzmann model with improved dissipation

Shear-Improved Smagorinsky Model for Large-Eddy Simulation of Wall-Bounded Turbulent Flows

A shear-improved Smagorinsky model is introduced based on recent results concerning shear effects in wall-bounded turbulence by Toschi et al. (2000). The Smagorinsky eddy-viscosity is modified subtracting the magnitude of the mean shear from the magnitude of the instantaneous resolved strain-rate…

Penetration of the blood-brain barrier and the anti-tumour effect of a novel PLGA-lysoGM1/DOX micelle drug delivery system

Effective treatment of glioma and other central nervous system (CNS) diseases is hindered by the presence of the blood-brain barrier (BBB). A novel nano-delivery vehicle system composed of PLGA-lysoGM1/DOX micelles was developed to cross the BBB for CNS treatment. We have shown that doxorubicin (…