Articolo in rivista

ADViSELipidomics: a workflow for analyzing lipidomics data

Summary: ADViSELipidomics is a novel Shiny app for preprocessing, analyzing and visualizing lipidomics data. It handles the outputs from LipidSearch and LIQUID for lipid identification and quantification and the data from the Metabolomics Workbench. ADViSELipidomics extracts information by parsing…

ESTIMATION AND GROUP VARIABLE SELECTION FOR ADDITIVE PARTIAL LINEAR MODELS WITH WAVELETS AND SPLINES

In this paper we study sparse high dimensional additive partial linear models with nonparametric additive components of heterogeneous smoothness. We review several existing algo- rithms that have been developed for this problem in the recent literature, highlighting the connec- tions between them,…

A Multiperiod Maximal Covering Location Model for the Optimal Location of Intersection Safety Cameras on an Urban Traffic Network

In this paper we propose a multiperiod optimization model based on the maximal covering location problem in order to support safety policies within urban areas. In particular, we focus on the field of car accidents control, by considering the problem of the optimal location of intersection safety…

A spatial model of cellular molecular trafficking including active transport along microtubules

Metabolite and lipoprotein profiles reveal sex-related oxidative stress imbalance in de novo drug-naive Parkinson's disease patients

Parkinson's disease (PD) is the neurological disorder showing the greatest rise in prevalence from 1990 to 2016. Despite clinical definition criteria and a tremendous effort to develop objective biomarkers, precise diagnosis of PD is still unavailable at early stage. In recent years, an increasing…

Numerical analysis of a first-order in time implicit-symplectic scheme for predator-prey systems

The numerical solution of reaction-diffusion systems modelling predator-prey dynamics using implicit-symplectic (IMSP) schemes is relatively new. When applied to problems with chaotic dynamics they perform well, both in terms of computational effort and accuracy. However, until the current paper, a…

Time-Scale Atoms Chains for Transients Detection in Audio Signals

This paper presents a novel approach for the extraction of the transients content of audio signals, usually represented as superposition of stationary, transient, and stochastic components. The proposed model exploits the predictable and peculiar time-scale behavior of transients by modeling them…

A comprehensive molecular interaction map for rheumatoid arthritis

Background: Computational biology contributes to a variety of areas related to life sciences and, due to the growing impact of translational medicine - the scientific approach to medicine in tight relation with basic science, it is becoming an important player in clinical-related areas. In this…

Influence of diffusion on the stability of a full Brusselator model

The classic Brusselator model consists of four reactions in- volving six components A, B, D, E, X, Y. In a typical run, the final products D and E are removed instantly, while, the con- centrations of the reactants A and B are kept constant. Then, the classic Brusselator model consisting of two…

Spin-geodesic deviations in the Schwarzschild spacetime