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Background
A subset of individuals affected by imprinting disorders displays multi-locus imprinting disturbances (MLID). MLID has been associated with maternal-effect variants that alter the maintenance of methylation at germline-derived differentially methylated regions (gDMRs) in early… |
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Vehicle routing and scheduling are two main issues in the hazardous material (hazmat) transportation problem. In this paper, we study the problem of managing a set of hazmat transportation requests in terms of hazmat shipment route selection and actual departure time definition. For each hazmat… |
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In this paper we present som eremarks about the Hilbert transform on the real line and its numerical approximation, in connection with its application in signal processing. |
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The ability of Well-Balanced (WB) schemes to capture very accurately
steady-state regimes of non-resonant hyperbolic systems of
balance laws has been thoroughly illustrated since its introduction
by Greenberg and LeRoux (1996) [15] (see also the anterior WB
Glimm scheme in E, 1992 [8]). This paper… |
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Internal waves describe the (linear) response of an incompressible sta- bly stratified fluid to small perturbations. The inclination of their group velocity with respect to the vertical is completely determined by their frequency. Therefore the reflection on a sloping boundary cannot follow… |
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A shear-improved Smagorinsky model is introduced based on recent results concerning shear effects in wall-bounded turbulence by Toschi et al. (2000). The Smagorinsky eddy-viscosity is modified subtracting the magnitude of the mean shear from the magnitude of the instantaneous resolved strain-rate… |
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Effective treatment of glioma and other central nervous system (CNS) diseases is hindered by the presence of the blood-brain barrier (BBB). A novel nano-delivery vehicle system composed of PLGA-lysoGM1/DOX micelles was developed to cross the BBB for CNS treatment. We have shown that doxorubicin (… |