Articolo in rivista

Modeling the Effect of High Calorie Diet on the Interplay between Adipose Tissue, Inflammation, and Diabetes

Background. Type 2 diabetes (T2D) is a chronic metabolic disease potentially leading to serious widespread tissue damage. Human organism develops T2D when the glucose-insulin control is broken for reasons that are not fully understood but have been demonstrated to be linked to the emergence of a…

A Hybrid With Cross-Entropy Method and Sequential Quadratic Programming to Solve Economic Load Dispatch Problem

This paper presents a new hybrid approach integrating the cross-entropy (CE) algorithm and the sequential quadratic programming (SQP) technique to solve the economic load dispatch (ELD) problem related to electrical power generating units. Due to the introduction of the valve-point effect in the…

Combustion dynamics in steady compressible flows

An inversion method based on random sampling for real-time MEG neuroimaging

The MagnetoEncephaloGraphy (MEG) has gained great interest in neurorehabilitation training due to its high temporal resolution. The challenge is to localize the active regions of the brain in a fast and accurate way. In this paper we use an inversion method based on random spatial sampling to solve…

Revisiting the stability of computing the roots of a quadratic polynomial

We show in this paper that the roots $x_1$ and $x_2$ of a scalar quadratic polynomial $ax^2 + bx + c = 0$ with real or complex coefficients $a, b, c$ can be computed in an element-wise mixed stable manner, measured in a relative sense. We also show that this is a stronger property than norm-wise…

ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design, and optimization

Vaccine research is a combinatorial science requiring computational analysis of vaccine components, formulations and optimization. We have developed a framework that combines computational tools for the study of immune function and vaccine development. This framework, named ImmunoGrid combines…

Computing the eigenvectors of nonsymmetric tridiagonal matrices

The computation of the eigenvalue decomposition of matrices is one of the most investigated problems in numerical linear algebra. In particular, real nonsymmetric tridiagonal eigenvalue problems arise in a variety of applications. In this paper the problem of computing an eigenvector corresponding…

A novel variant in the 3' untranslated region of the CDK4 gene: Interference with microRNA target sites and role in increased risk of cutaneous melanoma

Pedestrian flows in bounded domains with obstacles

Euler polynomials and the related quadrature rule

The use of Euler polynomials and Euler numbers allows us to construct a quadrature rule similar to the well-known Euler--MacLaurin quadrature formula, using Euler (instead of Bernoulli) numbers, and even (instead of odd) order derivatives of a given function evaluated at the extrema of the…